Page 182 - Concise Pathology for Exam Preparation ( PDFDrive )

7 Infections 167

Treponema pallidum
FIGURE 7.6. Demonstration of Treponema pallidum on FTA-ABS test.

Clinical Features
1. Primary stage
• The incubation period ranges from 10 to 90 days (average 21 days).
• The disease starts with a solitary, firm, nontender raised lesion (chancre; Fig. 7.7) on
penis, cervix, vagina, arms or as multiple sores (chancres). The chancre heals in a few
days (even without therapy).

Well defined
clean ulcer
(Chancre)

FIGURE 7.7. Primary chancre showing a typical clean, well-defined, indurated, nontender
ulcer.

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