Page 574 - Textbook of Pathology, 6th Edition

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SECTION III

Systemic Pathology

Figure 20.18 Gastric carcinoma, gross appearance of subtypes and their corresponding dominant histological patterns.

ii) Gastric distension and vomiting Gastric carcinoma remains undiagnosed until late when
iii) Loss of weight (cachexia) the symptoms appear. Therefore, the prognosis is generally
iv) Loss of appetite (anorexia) poor; 5-year survival rate being 5-15% from the time of
v) Anaemia, weakness, malaise. diagnosis of advanced gastric carcinoma. However, 5-year
The most common complication of gastric cancer is survival rate for early gastric carcinoma is far higher
haemorrhage (in the form of haematemesis and/or melaena); (93-99%) and hence the need for early diagnosis of the
others are obstruction, perforation and jaundice. condition.