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454                      Cardio Diabetes Medicine 2017







                        Idnetifying The Right Patients Who Benefits

                                        From  AICD Implantation





                                                     Dr.Raja Selvaraj
                                         Additional Professor, Department of Cardiology,
                                                      JIPMER, Puducherry





              Abstract:                                          critical to optimal utilisation of an AICD. This is based
              Sudden cardiac death is a major cause of mortality all   on identification of subgroups of patients who are at
              over the world and in India. It is all the more significant   high risk for sudden death in whom the risk of device
              because many of these patients are young and have   implantation  will  be less  than the benefit offered
              otherwise good quality of life.                    by  the  device.  This  article  discusses  the important
                                                                 indications  and major subgroups  who benefit from
              Ventricular arrhythmias have  been  established  as   AICD implant. This is not a comprehensive list of all
              the leading  cause of sudden cardiac  death. After   the indications.
              various anti-arrhythmic drugs were found to provide
              no protection against sudden death,  the automatic   Secondary prevention:
              implantable cardioverter  defibrillator  (AICD) has
              emerged  as  an effective method to prevent  sudden   Patients  who  have  survived a prior  cardiac  arrest
              death in patients at high risk. In this article, the key   are among  the  highest risk  groups  for having  a
              indications for implantation of an AICD are discussed   recurrent  cardiac arrest.  Pivotal studies  in  patients
              with the accompanying  evidence based on which     with  aborted sudden cardiac death  – AVID (2),  CIDS
              these indications have been made.                  and CASH  proved  the survival benefit  with AICD
                                                                 implantation  in this subgroup  of patients. Therefore
                                                                 this  remains  one  of  the most important indications
              Introduction:
                                                                 for AICD implantation.  Apart from patients with
              Sudden Cardiac Death is an unexpected natural death   cardiac arrest due to ventricular fibrillation, those with
              of cardiac causes occurring within a short period of   sustained ventricular tachycardia in the presence of
              onset of symptoms. It is  a major contributor  to all   structural heart disease are also considered for AICD
              death  and in India, has been estimated to account   implantation for secondary prevention.
              for about 10% of all deaths (1). When documented, the
              rhythm is found to be ventricular fibrillation in these   Thus secondary prevention is a class I indication
              patients. Defibrillation is an effective           for  AICD implant except for  one important caveat.
                                                                 Most important is  to exclude a reversible  cause for
              treatment  for  this rhythm,  but  most events occur   the cardiac arrest  in which  case AICD implantation
              outside  a hospital  setting  and immediate access to   is  not required. This  may occur, for  example,  in the
              defibrillation is not available.                   following settings -


              The Automatic Implantable                          1.   Ventricular fibrillation within 48 hours of acute
                                                                      myocardial infarction (primary VF).
              Cardioverter  Defibrillator  (AICD)  is  a miniaturised
              defibrillator which can be implanted in a patient, can   2.   Ventricular fibrillation in setting of hypokalemia
              sense fibrillation and provide immediate cardioversion.   or other electrolyte disturbances.
              It represents  an important technical  advance  in the   3.   Ventricular arrhythmias in the setting of acute
              management of these patients. However, the device       myocarditis that resolves with treatment.
              is  costly, implantation  is  an invasive procedure  and
              complications  can  occur  during implantation  and
              follow  up.  Therefore,  identifying  the right  patient is

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