Page 130 - Critical Care Notes
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4223_Tab03_107-130  29/08/14  8:28 AM  Page 124



                        RESP
          Later signs:
          ■ Chest pain, palpitations
          ■ Dysrhythmias
          ■ MI
          ■ Pulmonary edema
          ■ Throbbing headache, weakness, fatigue, dizziness, memory loss, ataxia,
            gait disturbances, confusion, inability to concentrate
          ■ Skin pale to reddish purple (not a reliable sign; “When you’re red, you’re
            dead.”)
          ■ Blurred vision, retinal hemorrhages
          ■ Tachypnea, dyspnea, respiratory alkalosis
          ■ Nausea, vomiting, lactic acidosis, rhabdomyolysis
          ■ Fecal and urinary incontinence
          ■ Upper airway obstruction: hoarseness, dry cough, DOE or labored breathing,
            stridor, difficulty swallowing
          ■ Brassy cough with carbonaceous (soot or carbon) sputum
          ■ Wheezing, bronchospasm
          ■ Hallucinations, seizures, syncope, coma when COHgb  ≥40%
          ■ Death possible if COHgb  ≥60%
          Diagnostic Tests
          Diagnostic testing is done not only to confirm the diagnosis of CO toxicity but
          also to determine complications.
          ■ COHgb and myoglobin concentration, methemoglobin
          ■ ABG (pulse oximetry SpO 2 inaccurate)
          ■ CO oximetry of an ABG sample or bedside pulse CO oximetry
          ■ ECG, CXR
          ■ CT to rule out cerebral edema and focal lesions
          ■ Troponin, CK, CK-MB, myoglobin
          ■ CBC and serum chemistry tests including electrolytes, glucose, BUN,
            creatinine, and liver function tests
          ■ Urinalysis
          ■ Toxicology screen, ethanol level, and cyanide levels possibly ordered
                              · ·
          ■ Fiberoptic bronchoscopy and V/Q scan
          Management
          ■ Assess respiratory and neurological status.
          ■ Monitor COHgb levels until <10%.
          ■ Administer 100% O 2 via rebreather mask or ETT (mechanical ventilation) to
            increase PaO 2 levels and decrease PaCO 2 levels. Pulse oximetry not valid.
          ■ Assess LOC using Glasgow Coma Scale.
          ■ Monitor pH level if lactic acidosis present.
          ■ Monitor cardiac status. Myocardial injury is a common consequence of
            moderate to severe CO poisoning → higher risk of death. Monitor for
            arrhythmias.
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