Page 66 - Critical Care Notes
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4223_Tab02_045-106  29/08/14  10:00 AM  Page 60



                  CV

                        Aortic Dissection
          Aortic dissection is a tear (without hematoma or an intramural hematoma) in
          the aortic wall that causes a longitudinal separation between the intima and
          adventitia layers resulting in diversion of blood flow from its normal arterial
          pathway. Aortic dissection requires emergency surgery.
                           Pathophysiology
          Tear in aorta intima → blood flows into subintimal region → pulsatile pressure
          creates a false channel between intimal and medial layers of aorta → intimal
          and medial layer is separated  → circulatory volume decreases  → channel
          expands and creates either an expanding mass or a hematoma (from blood
          coagulating)  → lumen narrows and obstructs blood flow, cardiac output
          decreases → results in end-organ failure, also diverted blood can pool around
          heart, resulting in cardiac tamponade.
                         Clinical Presentation

          Consider acute phase if diagnosed within first 2 wk of onset of pain.
          Presenting Symptoms
          ■ Mimics inferior wall MI
          ■ Standard type A aortic dissection: severe chest pain, sometimes sharp
          ■ Standard type B dissection: sudden, severe chest pain radiating to the back;
            described as “ripping or tearing” pain
          ■ Pain can shift to the abdomen
          ■ Increasing restlessness (sign of extending dissection)
          ■ Decrease in urine output
          ■ Anxiety: “feeling of doom”
          ■ Fainting or dizziness
          ■ Clammy skin
          ■ Nausea and vomiting
          ■ Pallor
          ■ Tachycardia, shortness of breath, orthopnea
          ■ Altered mental status and CVA-type symptoms
                           Diagnostic Tests
          ■ Chest x-ray: shows widening mediastinum
          ■ ECG
          ■ Transthoracic echocardiogram
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