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To the numerous authors who have toiled to create the chapters that constitute this book. Their energy and
                       perseverance are emblematic of their continued commitment to the value of scholarship and education
                       in medicine. The work of each of these authors enhances our knowledge of hematology, which ultimately
                       leads to improved care for patients with blood disorders. To my wife, Nan, and my children, Michael, Judith,
                       Daniel, and Margot, who continue to support my efforts and help me maintain a firm footing in life. To
                       President Barack Obama who has created a country in which I am happy to live and who will always be my
                       role model. To the members of my laboratory and clinical trials groups who make it a pleasure to come to
                       work each day. This edition would not have happened without the continued support of the staff at Elsevier,
                       especially Lucia Gunzel, who has made each edition significantly better and who provides the good cheer
                       that allows us to complete this book. I would also like to acknowledge my colleagues at the Icahn School of
                       Medicine at Mount Sinai School who continue to value the contribution that this book represents. Last, but
                       not least, our loyal readers, who have made this book a success for more than 25 years and continue to
                       value and use it in a manner that enhances their professional pursuits.
                                                                                        Ronald Hoffman, MD
                       To my wife, Peggy, for your support, inspiration, and partnership; to our children, Tim, Jenny, Julie, and
                       Rob, for your understanding; to our grandchildren for delighting us during this phase of our lives; to my
                       mentors, Art Parde, Arthur Nienhuis, Bernie Forget, and David Nathan, for your support and guidance; to
                       Addy Donnelly and Amy Thorp, for your incredible skill, patience, and good humor throughout this project;
                       and to the many patients and volunteers whose willingness to participate in clinical research made much of
                       the knowledge conveyed by this book possible.
                                                                                      Edward J. Benz, Jr., MD
                       To  my  friends  and  family  for  their  love  and  support;  to  my  mentors,  Eugene  M.  Berkman  and  Robert
                       S.  Schwartz,  who  have  provided  me  with  invaluable  guidance;  to  my  colleagues  at  the  University  of
                       Pennsylvania and Harvard, who have helped me develop academic transfusion medicine programs; and to
                       the trainees who make this endeavor enjoyable and worthwhile.
                                                                                      Leslie E. Silberstein, MD
                       To  my  family,  friends,  and  all  of  my  present  and  former  colleagues  and  trainees  for  their  support  and
                       encouragement; to all my mentors in hematology who have provided guidance, in particular, Michael Beard
                       and Malcolm Brenner.
                                                                                         Helen E. Heslop, MD
                       To my wife, Julia, for her love and unwavering support: I would be lost without her; to my children, Daniel
                       and Kyle, for their understanding and encouragement; to Gwen, for extending our family; to my colleagues
                       for  providing  me  with  an  environment  for  learning  and  growth;  and  to  my  trainees,  for  making  this  all
                       worthwhile.
                                                                                          Jeffrey I. Weitz, MD
                       To my respected clinical colleagues with appreciation for trusting me with the diagnostic material from their
                       patients; to my esteemed teachers, Jim Vardiman, Diana Variakojis, and from long ago, C. Robert Valeri,
                       for your many lessons focused on things at both ends of the microscope; and to my awesome trainees; it
                       is always a great pleasure to watch you grow to appreciate the serious, yet amazing, nature of our work.
                                                                                          John Anastasi, MD
                       I wish to express my appreciation to my family. I am grateful for the support, love, and inspiration from
                       Nahla, Youssef, and Farah.
                                                                                     Mohamed E. Salama, MD
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