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1428  Part X:  Malignant Myeloid Diseases                        Chapter 88:  Acute Myelogenous Leukemia             1429




                    847.  Minderman H, Zhou Y, O’Loughlin KL, Baer MR: Bortezomib activity and in vitro     876.  Seiter K, Feldman EJ, Dorota Halicka H, et al: Clinical and laboratory evaluation of
                     interactions with anthracyclines and cytarabine in acute myeloid leukemia cells are   all-trans retinoic acid modulation of chemotherapy in patients with acute myeloge-
                     independent of multidrug resistance mechanisms and p53 status. Cancer Chemother   nous leukaemia. Br J Haematol 108:40, 2000.
                     Pharmacol 60:245, 2007.                              877.  Chen Z, Wang Y, Wang W, et al: All-trans retinoic acid as a single agent induces com-
                    848.  Frelin C, Imbert V, Griessinger E, et al: Targeting NF-kappaB activation via pharma-  plete remission in a patient with acute leukemia of M2a subtype. Chin Med J 115:58,
                     cologic inhibition of IKK2-induced apoptosis of human acute myeloid leukemia cells.   2002.
                     Blood 105: 804, 2005.                                878.  Lehman S, Bengtzen S, Paul A, et al: Effects of arsenic trioxide (As O ) on leukemic
                                                                                                                   3
                                                                                                                  2
                    849.  Stone RM: Novel therapeutic agents in acute myeloid leukemia. Exp Hematol 35(Suppl   cells from patients with non-M3 acute myelogenous leukemia: Studies of cytotoxicity,
                     1):163, 2007.                                          apoptosis and the pattern of resistance. Eur J Haematol 66:357, 2001.
                    850.  Chalandon Y, Schwaller J: Targeting mutated protein tyrosine kinases and their sig-    879.  Ozturk A, Orhan B, Turken O, et al: Acute myeloblastic leukemia achieving complete
                     naling pathways in hematologic malignancies. Haematologica 90:949, 2005.  remission with amifostine alone. Leuk Lymphoma 43:451, 2002.
                    851.  Tamburini J, Chapuis N, Bardet V, et al: Mammalian target of rapamycin (mTOR)     880.  Steins MB, Padro T, Bieker R, et al: Efficacy and safety of thalidomide in patients with
                     inhibition activates phosphatidylinositol 3-kinase/Akt by up-regulating insulin-like   acute myeloid leukemia. Blood 99:834, 2002.
                     growth factor-1 receptor signaling in acute myeloid leukemia: Rationale for therapeu-    881.  Cabebe E, Wakelee H: Sunitinib: A newly approved small-molecule inhibitor of angio-
                     tic inhibition of both pathways. Blood 111:379, 2008.  genesis. Drugs Today (Barc) 42:387, 2006.
                    852.  Wei G, Twomey D, Lamb J, et al: Gene expression-based chemical genomics identifies     882.  Hatfield KJ, Olsnes AM, Gjertsen BT, Bruserud Ø: Antiangiogenic therapy in acute
                     rapamycin as a modulator of MCL1 and glucocorticoid resistance. Cancer Cell 10:331,   myelogenous leukemia: Targeting of vascular endothelial growth factor and interleu-
                     2006.                                                  kin 8 as possible antileukemic strategies. Curr Cancer Drug Targets 5:229, 2005.
                    853.  Kojima K, Shimanuki M, Shikami M, et al: The dual PI3 kinase/mTOR inhibitor     883.  Kitagawa M: The angiopoietin signaling pathway as a promising target for the treat-
                     PI-103 prevents p53 induction by Mdm2 inhibition but enhances p53-mediated mito-  ment of acute myeloid leukemia. Haematologica 91:1155B, 2006.
                     chondrial apoptosis in p53 wild-type AML. Leukemia 22:1728, 2008.    884.  Lancet JE, List AF, Moscinski LC, et al: Treatment of deletion 5q acute myeloid leuke-
                    854.  Martelli AM, Nyåkern M, Tabellini G, et al: Phosphoinositide 3-kinase/Akt signaling   mia with lenalidomide. Leukemia 21:586, 2007.
                     pathway and its therapeutical implications for human acute myeloid leukemia. Leuke-    885.  Burger JA, Bürkle A: The CXCR4 chemokine receptor in acute and chronic leukaemia:
                     mia 20:911, 2006.                                      A marrow homing receptor and potential therapeutic target. Br J Haematol 137:288,
                    855.  Papa V, Tazzari PL, Chiarini F, et al: Proapoptotic activity and chemosensitizing effect   2007.
                     of the novel Akt inhibitor perifosine in acute myelogenous leukemia cells. Leukemia     886.  Zeng Z, Samudio IJ, Munsell M, et al: Inhibition of CXCR4 with the novel RCP168
                     22:147, 2008.                                          peptide overcomes stroma-mediated chemoresistance in chronic and acute leuke-
                    856.  Milella M, Kornblau SM, Estrov Z, et al: Therapeutic targeting of the MEK/MAPK   mias. Mol Cancer Ther 5:3113, 2006.
                     signal transduction module in acute myeloid leukemia. J Clin Invest 108:851, 2001.    887.  Andreeff M, Konopleva M: Mechanisms of drug resistance in AML. Cancer Treat Res
                    857.  Ikezoe T, Yang J, Nishioka C, et al: A novel treatment strategy targeting Aurora kinases   112:237, 2002.
                     in acute Myelogenous leukemia. Mol Cancer Ther 6:1851, 2007.    888.  Van der Kolk DM, De Vries EG, Muller M, Vellenga E: The role of drug efflux pumps
                    858.  Thomas X, Campos L, Le QH, Guyotat D: Heat shock proteins and acute leukemias.   in acute myeloid leukemia. Leuk Lymphoma 43:685, 2002.
                     Hematology 10:225, 2005.                             889.  Claxton D, Choudhury A: Potential for therapy with AML-derived dendritic cells.
                    859.  Hu S, Niu H, Minkin P, et al: Comparison of antitumor effects of multitargeted   Leukemia 15:668, 2001.
                     tyrosine kinase inhibitors in acute myelogenous leukemia. Mol Cancer Ther 7:1110,     890.  Rosenblatt J, Avigan D: Can leukemia-derived dendritic cells generate antileukemia
                     2008.                                                  immunity? Expert Rev Vaccines 5:467, 2006.
                    860.  Raanani P, Shpilberg O, Ben-Bassat I, et al: Extramedullary disease and targeted ther-    891.  Panoskaltsis N: Dendritic cells in MDS and AML—Cause, effect or solution to the
                     apies for hematological malignancies—Is the association real? Ann Oncol 18:7, 2007.  immune pathogenesis of disease? Leukemia 19:354, 2005.
                    861.  Shangary S, Johnson DE: Recent advances in the development of anticancer agents     892.  Woiciechowsky A, Regn S, Kolb H-J, Roskrow M: Leukemic dendritic cells generated
                     targeting cell death inhibitors in the Bcl-2 protein family. Leukemia 17:1470, 2003.  in the presence of FLT3 ligand have the capacity to stimulate an autologous leuke-
                    862.  Konopleva M, Contractor R, Tsao T, et al: Mechanisms of apoptosis sensitivity and   mia-specific cytotoxic T cell response from patients with acute myeloid leukemia.
                     resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia.  Cancer Cell   Leukemia 15:246, 2001.
                     10:375, 2006.                                        893.  Stripecke R, Levine AM, Pullarkat V, Cardoso AA: Immunotherapy with acute leu-
                    863.  Konopleva M, Watt J, Contractor R, et al: Mechanisms of antileukemic activity of the   kemia cells modified into antigen-presenting cells: Ex vivo culture and gene transfer
                     novel Bcl-2 homology domain-3 mimetic GX15–070 (obatoclax). Cancer Res 68:3413,   methods. Leukemia 16:1974, 2002.
                     2008.                                                894.  Galea-Lauri J, Darling D, Mufti G, et al: Eliciting cytotoxic T lymphocytes against
                    864.  Konopleva M, Tsao T, Ruvolo P, et al: Novel triterpenoid CDDO-Me is a potent   acute myeloid leukemia-derived antigens: Evaluation of dendritic cell-leukemia cell
                     inducer of apoptosis and differentiation in acute myelogenous leukemia. Blood 99:326,   hybrids and other antigen-loading strategies for dendritic cell-based vaccination.
                     2002.                                                  Cancer Immunol Immunother 51:299, 2002.
                    865.  Morgan MA, Ganser A, Reuter CWM: Therapeutic efficacy of prenylation inhibitors     895.  Cooper MA, Caligiuri MA: Immunologic manipulation in AML: From bench to bed-
                     in the treatment of myeloid leukemia. Leukemia 17:1482, 2003.  side. Leukemia 16:736, 2002.
                    866.  Kurzrock R, Cortes J, Kantarjian H: Clinical development of farnesyltransfer-    896.  Meloni G, Trisolini SM, Capria S, et al: How long can we give interleukin-2? Clinical
                     ase inhibitors in leukemias and myelodysplastic syndrome.  Semin  Hematol 39:20,     and immunological evaluation of AML patients after 10 or more years of IL2 admin-
                     2002.                                                  istration. Leukemia 16:2016, 2002.
                    867.  Brunner TB, Hahn SM, Gupta AK, et al: Farnesyltransferase inhibitors: An overview     897.  Baer MR, George SL, Caligiuri MA, et al: Low-dose interleukin-2 immunotherapy
                     of the results of preclinical and clinical investigations. Cancer Res 63:5656, 2003.  does not improve outcome of patients age 60 years and older with acute myeloid leu-
                    868.  Karp JE, Lancet JE, Kaufmann SH, et al: Clinical and biologic activity of the farnesyl-  kemia in first complete remission: Cancer and Leukemia Group B Study 9720. J Clin
                     transferase inhibitor R115777 in adults with refractory and relapsed acute leukemias:   Oncol 26:4934, 2008.
                     A phase 1 clinical-laboratory correlative trial. Blood 97:3361, 2001.    898.  Elisseeva OA, Oka Y, Tsuboi A, et al: Humoral immune responses against Wilms
                    869.  Minden MD, Dimitroulakos J, Nohynek D, Penn LZ: Lovastatin induced control of   tumor gene WT1 product in patients with hematopoietic malignancies.  Blood
                     blast cell growth in an elderly patient with acute myeloblastic leukemia. Leuk Lym-  99:3272, 2002.
                     phoma 40:659, 2001.                                  899.  Molldrem J: Immune therapy of AML. Cytotherapy 4:437, 2002.
                    870.  Lishner M, Bar-Sef A, Elis A, Fabian I: Effect of simvastatin alone and in combination     900.  Norde WJ, Hobo W, van der Voort R, et al: Coinhibitory molecules in hematologic
                     with cytosine arabinoside on the proliferation of myeloid leukemia cell lines. J Investig   malignancies: Targets for therapeutic intervention. Blood 120:728, 2012.
                     Med 49:319, 2001.                                    901.  Choo A, Palladinetti P, Holmes T, et al: SiRNA targeting the IRF2 transcription factor
                    871.  Li HY, Appelbaum FR, Willman CL, et al: Cholesterol-modulating agents kill acute   inhibits leukaemic cell growth. Int J Oncol 33:175, 2008.
                     myeloid leukemia cells and sensitize them to therapeutics by blocking adaptive cho-    902.  Klisovic RB, Blum W, Wei X, et al: Phase I study of GTI-2040, an antisense to ribonu-
                     lesterol responses. Blood 101:3628, 2003.              cleotide reductase, in combination with high-dose cytarabine in patients with acute
                    872.  Munker R, Kobayashi T, Eistner E, et al: A new series of vitamin D analogs is highly   myeloid leukemia. Clin Cancer Res 14:3889, 2008.
                     active for clonal inhibition, differentiation, and induction of WAF1 in myeloid leuke-    903.  Stevenson GT: CD38 as a therapeutic target. Mol Med 12:345, 2006.
                     mia. Blood 88:2201, 1996.                            904.  Abutalib SA, Tallman MS: Monoclonal antibodies for the treatment of acute myeloid
                    873.  Morosetti R, Grignani F, Liberatore C, et al: Infrequent alterations of the RAR alpha   leukemia. Curr Pharm Biotechnol 7:343, 2006.
                     gene in acute myelogenous leukemias, retinoic acid-resistant acute promyelocytic leu-    905.  Wayne AS, FitzGerald DJ, Kreitman RJ, et al: Immunotoxins for leukemia.  Blood
                     kemias, myelodysplastic syndromes, and cell lines. Blood 87:4399, 1996.  123:2470, 2014.
                    874.  Usuki K, Kitazume K, Endo M, et al: Combination therapy with granulocyte colony-    906.  Curti A, Ruggeri L, D’Addio A, et al: Successful transfer of alloreactive haploidenti-
                     stimulating factor, all-trans retinoic acid, and low-dose cytotoxic drugs for acute mye-  cal KIR ligand-mismatched natural killer cells after infusion in elderly after high risk
                     logenous leukemia. Intern Med 34:1186, 1995.           acute myeloid leukemia patients. Blood 11:3273, 2011.
                    875.  Zhang W, Piatyszek MA, Kobayashi T, et al: Telomerase activity in human acute     907.  Sekeres MA, Gundacker H, Lancet J, et al: A phase 2 study of lenalidomide monother-
                     myelogenous leukemia: Inhibition of telomerase activity by differentiation-inducing   apy in patients with 5q acute myeloid leukemia: Southwest Oncology Group Study
                     agents. Clin Cancer Res 2:799, 1996.                   S0605. Blood 118: 523, 2011.







          Kaushansky_chapter 88_p1373-1436.indd   1429                                                                  9/21/15   11:02 AM
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