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2186  Part XII:  Hemostasis and Thrombosis  Chapter 127:  Antibody-mediated Coagulation Factor Deficiencies          2187




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                  THE PROTEIN C SYSTEM                                    16.  Gouw SC, van der Bom JG, Marijke van den Berg H: Treatment-related risk factors
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                  disorder has been reported,  but evidently is rare. In contrast, there     17.  Astermark J, Berntorp E, White GC, et al: The Malmo International Brother Study
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                  with acquired protein S deficiency.  Anti–protein S antibodies, but not     18.  Astermark J, Oldenburg J, Escobar M, et al: The Malmo International Brother Study
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                                     2
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                  mutation, and for deep venous thrombosis.  Additionally, antibodies to     20.  Oldenburg J, Schroder J, Brackmann HH, et al: Environmental and genetic factors
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                  ACQUIRED ANTIBODIES TO OTHER                            22.  Hendrickson JE, Chadwick TE, Roback JD, et al: Inflammation enhances consump-
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                                                                          23.  Meeks SL, Healey JF, Parker ET, et al: Antihuman factor VIII C2 domain antibodies in
                  Clinically significant antibodies to coagulation factors other than factor   hemophilia A mice recognize a functionally complex continuous spectrum of epitopes
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                  ders are sufficiently rare that they merit case reports, which are only     24.  Stowell SR, Henry KL, Smith NH, et al: Alloantibodies to a paternally derived RBC
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                  hemophilia B is extremely rare. 92,93  Patients with antifibrinogen anti-    25.  Martin F, Kearney JF: Marginal-zone B cells. Nat Rev Immunol 2(5):323–335, 2002.
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          Kaushansky_chapter 127_p2183-2190.indd   2187                                                                 17/09/15   3:44 pm
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