Page 2240 - Williams Hematology ( PDFDrive )
P. 2240

2214  Part XII:  Hemostasis and Thrombosis            Chapter 129:  Disseminated Intravascular Coagulation           2215




                    48.  Versteeg HH, Peppelenbosch MP, Spek CA: The pleiotropic effects of tissue factor: A     82.  Lay AJ, Donahue D, Tsai MJ, et al: Acute inflammation is exacerbated in mice geneti-
                     possible role for factor VIIa-induced intracellular signalling? Thromb Haemost 86:1353,   cally predisposed to a severe protein C deficiency. Blood 109:1984, 2007.
                     2001.                                                83.  Feistritzer C, Sturn DH, Kaneider NC, et al: Endothelial protein C receptor-depen-
                    49.  Levi M, de Jonge E, van der Poll T: Rationale for restoration of physiological anticoag-  dent inhibition of human eosinophil chemotaxis by protein C. J Allergy Clin Immunol
                     ulant pathways in patients with sepsis and disseminated intravascular coagulation. Crit   112:375, 2003.
                     Care Med 29:S90, 2001.                               84.  Sturn DH, Kaneider NC, Feistritzer C, et al: Expression and function of the endothelial
                    50.  Szaba FM, Smiley ST: Roles for thrombin and fibrin(ogen) in cytokine/chemokine pro-  protein C receptor in human neutrophils. Blood 102:1499, 2003.
                     duction and macrophage adhesion in vivo. Blood 99:1053, 2002.    85.  Hoffmann JN, Vollmar B, Laschke MW, et al: Microhemodynamic and cellular mech-
                    51.  Levi M, van der Poll T: The role of natural anticoagulants in the pathogenesis and man-  anisms of activated protein C action during endotoxemia.  Crit Care Med 32:1011,
                     agement of systemic activation of coagulation and inflammation in critically ill patients.   2004.
                     Semin Thromb Hemost 34:459, 2008.                    86.  Nick JA, Coldren CD, Geraci MW, et al: Recombinant human activated protein C
                    52.  Levi M: Antithrombin in sepsis revisited. Crit Care 9:624, 2005.  reduces human endotoxin-induced pulmonary inflammation via inhibition of neu-
                    53.  Levi M, van der Poll T: Two-way interactions between inflammation and coagulation.   trophil chemotaxis. Blood 104:3878, 2004.
                     Trends Cardiovasc Med 15:254, 2005.                  87.  Shimizu S, Gabazza EC, Taguchi O, et al: Activated protein C inhibits the expression of
                    54.  Kobayashi M, Shimada K, Ozawa T: Human recombinant interleukin-1 beta- and   platelet-derived growth factor in the lung. Am J Respir Crit Care Med 167:1416, 2003.
                     tumor necrosis factor alpha-mediated suppression of heparin-like compounds on cul-    88.  Zeng W, Matter WF, Yan SB, et al: Effect of drotrecogin alfa (activated) on human endo-
                     tured porcine aortic endothelial cells. J Cell Physiol 144:383, 1990.  thelial cell permeability and Rho kinase signaling. Crit Care Med 32:S302, 2004.
                    55.  Levi M, van der Poll T: Recombinant human activated protein C: Current insights into     89.  Feistritzer C, Riewald M: Endothelial barrier protection by activated protein C through
                     its mechanism of action. Crit Care 11 Suppl 5:S3, 2007.  PAR1-dependent sphingosine 1-phosphate receptor-1 cross activation. Blood 105:3178,
                    56.  Esmon CT: Role of coagulation inhibitors in inflammation. Thromb Haemost 86:51,   2005.
                     2001.                                                90.  Finigan JH, Dudek SM, Singleton PA, et al: Activated protein C mediates novel lung
                    57.  Esmon  CT:  The regulation  of natural anticoagulant  pathways.  Science  235:1348,    endothelial barrier enhancement: Role of sphingosine 1-phosphate receptor transacti-
                     1987.                                                 vation. J Biol Chem 280:17286, 2005.
                    58.  Esmon CT: The endothelial cell protein C receptor. Thromb Haemost 83:639, 2000.    91.  Cheng T, Liu D, Griffin JH, et al: Activated protein C blocks p53-mediated apoptosis in
                    59.  Mesters RM, Helterbrand J, Utterback BG, et al: Prognostic value of protein C concen-  ischemic human brain endothelium and is neuroprotective. Nat Med 9:338, 2003.
                     trations in neutropenic patients at high risk of severe septic complications. Crit Care     92.  Riewald M, Petrovan RJ, Donner A, et al: Activation of endothelial cell protease acti-
                     Med 28:2209, 2000.                                    vated receptor 1 by the protein C pathway. Science 296:1880, 2002.
                    60.  Vary TC, Kimball SR: Regulation of hepatic protein synthesis in chronic inflammation     93.  Mosnier LO, Griffin JH: Inhibition of staurosporine-induced apoptosis of endothelial
                     and sepsis. Am J Physiol 262:C445, 1992.              cells by activated protein C requires protease activated receptor-1 and endothelial cell
                    61.  Eckle I, Seitz R, Egbring R, et al: Protein C degradation in vitro by neutrophil elastase.   protein C receptor. Biochem J 373:65, 2003.
                     Biol Chem Hoppe Seyler 372:1007, 1991.               94.  Mosnier LO, Zlokovic BV, Griffin JH: The cytoprotective protein C pathway.  Blood
                    62.  Nawroth PP, Stern DM: Modulation of endothelial cell hemostatic properties by tumor   109:3161, 2007.
                     necrosis factor. J Exp Med 163:740, 1986.            95.  Biemond BJ, Levi M, ten Cate H, et al: Plasminogen activator and plasminogen acti-
                    63.  Faust SN, Levin M, Harrison OB, et al: Dysfunction of endothelial protein C activation   vator inhibitor I release during experimental endotoxaemia in chimpanzees: Effect of
                     in severe meningococcal sepsis. N Engl J Med 345:408, 2001.  interventions in the cytokine and coagulation cascades. Clin Sci 88:587, 1995.
                    64.  Taylor FB Jr, Dahlback B, Chang AC, et al: Role of free protein S and C4b binding pro-    96.  Schleef RR, Bevilacqua MP, Sawdey M, et al: Cytokine activation of vascular endothe-
                     tein in regulating the coagulant response to Escherichia coli. Blood 86:2642, 1995.  lium. Effects on tissue-type plasminogen activator and type 1 plasminogen activator
                    65.  Taylor FB Jr, Stearns-Kurosawa DJ, Kurosawa S, et al: The endothelial cell protein C   inhibitor. J Biol Chem 263:5797, 1988.
                     receptor aids in host defense against Escherichia coli sepsis. Blood 95:1680, 2000.    97.  van Hinsbergh VW, Kooistra T, van den Berg EA, et al: Tumor necrosis factor increases
                    66.  De Pont AC, Bakhtiari K, Hutten BA, et al: Endotoxaemia induces resistance to acti-  the production of plasminogen activator inhibitor in human endothelial cells in vitro
                     vated protein C in healthy humans. Br J Haematol 134:213, 2006.  and in rats in vivo. Blood 72:1467, 1988.
                    67.  de Jonge E, Dekkers PE, Creasey AA, et al: Tissue factor pathway inhibitor (TFPI)     98.  Asakura H, Ontachi Y, Mizutani T: An enhanced fibrinolysis prevents the development
                     dose-dependently inhibits coagulation activation without influencing the fibrinolytic   of multiple organ failure in disseminated intravascular coagulation in spite of much
                     and cytokine response during human endotoxemia. Blood 95:1124, 2000.  activation of blood coagulation. Crit Care Med 29:1164, 2001.
                    68.  Creasey AA, Chang AC, Feigen L, et al: Tissue factor pathway inhibitor reduces mortal-    99.  Yamamoto K, Loskutoff DJ: Fibrin deposition in tissues from endotoxin-treated mice
                     ity from Escherichia coli septic shock. J Clin Invest 91:2850, 1993.  correlates with decreases in the expression of urokinase-type but not tissue-type plas-
                    69.  Roemisch J, Gray E, Hoffmann JN, et al: Antithrombin: A new look at the actions of a   minogen activator. J Clin Invest 97:2440, 1996.
                     serine protease inhibitor. Blood Coagul Fibrinolysis 13:657, 2002.    100. Nesheim M, Wang W, Boffa M, et al: Thrombin, thrombomodulin and TAFI in the
                    70.  Opal SM: Interactions between coagulation and inflammation.  Scand J Infect Dis   molecular link between coagulation and fibrinolysis. Thromb Haemost 78:386, 1997.
                     35:545, 2003.                                        101. Salvemini D, Cuzzocrea S: Oxidative stress in septic shock and disseminated intravas-
                    71.  Harada N, Okajima K, Kushimoto S, et al: Antithrombin reduces ischemia/reperfusion   cular coagulation. Free Radic Biol Med 33:1173, 2002.
                     injury of rat liver by increasing the hepatic level of prostacyclin. Blood 93:157, 1999.    102. Asakura H, Okudaira M, Yoshida T: Induction of vasoactive substances differs in
                    72.  Horie S, Ishii H, Kazama M: Heparin-like glycosaminoglycan is a receptor for antith-  LPS-induced and TF-induced DIC models in rats. Thromb Haemost 88:663, 2002.
                     rombin III-dependent but not for thrombin-dependent prostacyclin production in     103. Levi M, Nieuwdorp M, van der Poll T, et al: Metabolic modulation of inflammation-in-
                     human endothelial cells. Thromb Res 59:895, 1990.     duced activation of coagulation. Semin Thromb Hemost 34:26, 2008.
                    73.  Mizutani A, Okajima K, Uchiba M, et al: Antithrombin reduces ischemia/reperfu-    104. Kjalke M, Silveira A, Hamsten A, et al: Plasma lipoproteins enhance tissue factor-inde-
                     sion-induced renal injury in rats by inhibiting leukocyte activation through promotion   pendent factor VII activation. Arterioscler Thromb Vasc Biol 20:1835, 2000.
                     of prostacyclin production. Blood 101:3029, 2003.    105. van der Poll T, Coyle SM, Levi M, et al: Fat emulsion infusion potentiates coagulation
                    74.  Uchiba M, Okajima K, Murakami K: Effects of various doses of antithrombin III on   activation during human endotoxemia. Thromb Haemost 75:83, 1996.
                     endotoxin-induced endothelial cell injury and coagulation abnormalities in rats.     106. Pajkrt D, Lerch PG, van der Poll T, et al: Differential effects of reconstituted high-den-
                     Thromb Res 89:233, 1998.                              sity lipoprotein on coagulation, fibrinolysis and platelet activation during human endo-
                    75.  Esmon CT: New mechanisms for vascular control of inflammation mediated by natural   toxemia. Thromb Haemost 77:303, 1997.
                     anticoagulant proteins. J Exp Med 196:561, 2002.     107. Birjmohun RS, van Leuven SI, Levels JH, et al: High-density lipoprotein attenuates
                    76.  Okajima K: Regulation of inflammatory responses by natural anticoagulants. Immunol   inflammation and coagulation response on endotoxin challenge in humans. Arterio-
                     Rev 184:258, 2001.                                    scler Thromb Vasc Biol 27:1153, 2007.
                    77.  Taylor FB Jr, Chang A, Esmon CT, et al: Protein C prevents the coagulopathic and lethal     108. Bisoendial RJ, Kastelein JJ, Peters SL, et al: Effects of CRP infusion on endothelial func-
                     effects of Escherichia coli infusion in the baboon. J Clin Invest 79:918, 1987.  tion and coagulation in normocholesterolemic and hypercholesterolemic subjects. J
                    78.  Hancock WW, Tsuchida A, Hau H, et al: The anticoagulants protein C and protein S   Lipid Res 48:952, 2007.
                     display potent antiinflammatory and immunosuppressive effects relevant to transplant     109. Grant PJ: Diabetes mellitus as a prothrombotic condition. J Intern Med 262:157, 2007.
                     biology and therapy. Transplant Proc 24:2302, 1992.    110. Juhan-Vague I, Roul C, Alessi MC, et al: Increased plasminogen activator inhibitor
                    79.  Hancock WW, Grey ST, Hau L, et al: Binding of activated protein C to a specific recep-  activity in non insulin dependent diabetic patients—Relationship with plasma insulin.
                     tor on human mononuclear phagocytes inhibits intracellular calcium signaling and   Thromb Haemost 61:370, 1989.
                     monocyte-dependent proliferative responses. Transplantation 60:1525, 1995.    111. Mansfield MW, Stickland MH, Grant PJ: PAI-1 concentrations in first-degree relatives
                    80.  White B, Schmidt M, Murphy C, et al: Activated protein C inhibits lipopolysaccha-  of patients with non-insulin-dependent diabetes: Metabolic and genetic associations.
                     ride-induced nuclear translocation of nuclear factor kappaB (NF-kappaB) and tumour   Thromb Haemost 77:357, 1997.
                     necrosis factor alpha (TNF-alpha) production in the THP-1 monocytic cell line. Br J     112. Samad F, Pandey M, Loskutoff DJ: Regulation of tissue factor gene expression in obe-
                     Haematol 110:130, 2000.                               sity. Blood 98:3353, 2001.
                    81.  Levi M, Dorffler-Melly J, Reitsma PH, et al: Aggravation of endotoxin-induced dis-    113. Stegenga ME, van der Crabben SN, Levi M, et al: Hyperglycemia enhances coagulation
                     seminated intravascular coagulation and cytokine activation in heterozygous protein C   and reduces neutrophil degranulation, whereas hyperinsulinemia inhibits fibrinolysis
                     deficient mice. Blood 101:4823, 2003.                 during human endotoxemia. Blood 112:82, 2008.







          Kaushansky_chapter 129_p2199-2220.indd   2215                                                                 17/09/15   3:46 pm
   2235   2236   2237   2238   2239   2240   2241   2242   2243   2244   2245