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374 Part V: Therapeutic Principles Chapter 23: Hematopoietic Cell Transplantation 375
Stanford investigators used TLI-ATG conditioning in 16 living-donor 29. Osawa M, Hanada K, Hamada H, et al: Long-term lymphohematopoietic reconstitution
kidney transplant recipients from HLA-matched siblings treated with by a single CD34-low/negative hematopoietic stem cell. Science 273:242–245, 1996.
infusion of CD34-selected hematopoietic progenitor cells and a defined 30. Baum CM, Weissman IL, Tsukamoto AS, et al: Isolation of a candidate human hemato-
poietic stem-cell population. Proc Natl Acad Sci U S A 89:2804–2808, 1992.
dose of T cells. Fifteen patients developed multilineage mixed chimer- 31. Negrin RS, Atkinson K, Leemhuis T, et al: Transplantation of highly purified
ism without GVHD, and eight were withdrawn from antirejection medi- CD34+Thy-1+ hematopoietic stem cells in patients with metastatic breast cancer. Biol
Blood Marrow Transplant 6:262–271, 2000.
cations without subsequent rejection episodes. Four additional chimeric 32. Vose JM, Bierman PJ, Lynch JC, et al: Transplantation of highly purified CD34+Thy-1+
patients were in the midst of drug withdrawal, and only four patients hematopoietic stem cells in patients with recurrent indolent non-Hodgkin’s lymphoma.
were not withdrawn because of the return of the underlying disease or Biol Blood Marrow Transplant 7:680–687, 2001.
rejection episodes. 189,443 Case reports have also described the use of allo- 33. Michallet M, Philip T, Philip I, et al: Transplantation with selected autologous periph-
geneic HCT as a tolerance-induction platform in lung transplantation. 444 eral blood CD34+Thy1+ hematopoietic stem cells (HSCs) in multiple myeloma: Impact
of HSC dose on engraftment, safety, and immune reconstitution. Exp Hematol 28:858–
870, 2000.
34. Muller AM, Kohrt HE, Cha S, et al: Long-term outcome of patients with metastatic
REFERENCES breast cancer treated with high-dose chemotherapy and transplantation of purified
autologous hematopoietic stem cells. Biol Blood Marrow Transplant 18:125–133, 2012.
1. Osgood EE, Riddle MC, Mathews TJ: Aplastic anemia treated with daily transfusions 35. Muller AM, Shashidhar S, Kupper NJ, et al: Co-transplantation of pure blood stem cells
and intravenous marrow. Ann Intern Med 13:357–367, 1939. with antigen-specific but not bulk T cells augments functional immunity. Proc Natl
2. Fabricius-Moller J: Experimental Studies on the Hemorrhagic Diathesis of X-Ray Sick- Acad Sci U S A 109:5820–5825, 2012.
ness. Levin and Munksgards Forlag, Copenhagen, 1922. 36. Hidalgo A, Robledo MM, Teixido J: CD44-mediated hematopoietic progenitor cell
3. Jacobson LO, Marks EK, Robson MJ: The effect of spleen protection on mortality fol- adhesion and its complex role in myelopoiesis. J Hematother Stem Cell Res 11:539–547,
lowing X-irradiation. J Lab Clin Med 34:1538, 1949. 2002.
4. Lorenz E, Uphoff D, Reid TR, et al: Modification of irradiation injury in mice and 37. Frenette PS, Subbarao S, Mazo IB, et al: Endothelial selectins and vascular cell adhesion
guinea pigs by bone marrow injections. J Natl Cancer Inst 12:197–201, 1951. molecule-1 promote hematopoietic progenitor homing to bone marrow. Proc Natl Acad
5. Cole LJ, Fishler MC, Bond VP: Subcellular fractionation of mouse spleen radiation pro- Sci U S A 95:14423–14428, 1998.
tection activity. Proc Natl Acad Sci U S A 39:759–772, 1953. 38. Katayama Y, Hidalgo A, Furie BC, et al: PSGL-1 participates in E-selectin-mediated
6. Hilfinger MF Jr, Ferguson JH, Riemenschneider PA: The effect of homologous bone mar- progenitor homing to bone marrow: Evidence for cooperation between E-selectin lig-
row emulsion on rabbits after total body irradiation. J Lab Clin Med 42:581–591, 1953. ands and alpha4 integrin. Blood 102:2060–2067, 2003.
7. Lorenz E, Congdon CC: Modification of lethal irradiation injury in mice by injection of 39. Papayannopoulou T, Craddock C, Nakamoto B, et al: The VLA4/VCAM-1 adhe-
homologous or heterologous bone. J Natl Cancer Inst 14:955–965, 1954. sion pathway defines contrasting mechanisms of lodgement of transplanted murine
8. Barnes DWH, Loutit JF: Spleen Protection: The Cellular Hypothesis. Butterworth, Lon- hemopoietic progenitors between bone marrow and spleen. Proc Natl Acad Sci U S A
don, 1955. 92:9647–9651, 1995.
9. Barnes DW, Corp MJ, Loutit JF, et al: Treatment of murine leukaemia with X rays and 40. Vermeulen M, Le Pesteur F, Gagnerault MC, et al: Role of adhesion molecules in the
homologous bone marrow; preliminary communication. Br Med J 2:626–627, 1956. homing and mobilization of murine hematopoietic stem and progenitor cells. Blood
10. Thomas ED, Lochte HL Jr, Lu WC, et al: Intravenous infusion of bone marrow in 92:894–900, 1998.
patients receiving radiation and chemotherapy. N Engl J Med 257:491–496, 1957. 41. Hirsch E, Iglesias A, Potocnik AJ, et al: Impaired migration but not differentiation of
11. Thomas ED, Lochte HL Jr, Cannon JH, et al: Supralethal whole body irradiation and haematopoietic stem cells in the absence of beta1 integrins. Nature 380:171–175, 1996.
isologous marrow transplantation in man. J Clin Invest 38:1709–1716, 1959. 42. Nagasawa T, Hirota S, Tachibana K, et al: Defects of B-cell lymphopoiesis and
12. Mathe G, Jammet H, Pendic B, et al: [Transfusions and grafts of homologous bone mar- bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1. Nature
row in humans after accidental high dosage irradiation] [in French]. Rev Fr Etud Clin 382:635–638, 1996.
Biol 4:226–238, 1959. 43. Lapidot T: Mechanism of human stem cell migration and repopulation of NOD/SCID
13. Kurnick NB, Montano A, Gerdes JC, et al: Preliminary observations on the treatment of and B2mnull NOD/SCID mice. The role of SDF-1/CXCR4 interactions. Ann N Y Acad
postirradiation hematopoietic depression in man by the infusion of stored autogenous Sci 938:83–95, 2001.
bone marrow. Ann Intern Med 49:973–986, 1958. 44. Liles WC, Broxmeyer HE, Rodger E, et al: Mobilization of hematopoietic progenitor
14. Haurani FI: Thirty-one-year survival following chemotherapy and autologous bone cells in healthy volunteers by AMD3100, a CXCR4 antagonist. Blood 102:2728–2730,
marrow in malignant lymphoma. Am J Hematol 55:35–38, 1997. 2003.
15. Bortin MM: A compendium of reported human bone marrow transplants. Transplan- 45. Jung Y, Wang J, Song J, et al: Annexin II expressed by osteoblasts and endothelial cells
tation 9:571–587, 1970. regulates stem cell adhesion, homing, and engraftment following transplantation. Blood
16. Gatti RA, Meuwissen HJ, Allen HD, et al: Immunological reconstitution of sex-linked 110:82–90, 2007.
lymphopenic immunological deficiency. Lancet 2:1366–1369, 1968. 46. Calvi LM, Adams GB, Weibrecht KW, et al: Osteoblastic cells regulate the haematopoi-
17. De Koning J, Van Bekkum DW, Dicke KA, et al: Transplantation of bone-marrow cells etic stem cell niche. Nature 425:841–846, 2003.
and fetal thymus in an infant with lymphopenic immunological deficiency. Lancet 47. Mendez-Ferrer S, Michurina TV, Ferraro F, et al: Mesenchymal and haematopoietic
1:1223–1227, 1969. stem cells form a unique bone marrow niche. Nature 466:829–834, 2010.
18. Bach FH, Albertini RJ, Joo P, et al: Bone-marrow transplantation in a patient with the 48. Masuda S, Ageyama N, Shibata H, et al: Cotransplantation with MSCs improves
Wiskott-Aldrich syndrome. Lancet 2:1364–1366, 1968. engraftment of HSCs after autologous intra-bone marrow transplantation in nonhu-
19. Bortin MM, Bach FH, van Bekkum DW, et al: 25th anniversary of the first successful man primates. Exp Hematol 37:1250–1257.e1, 2009.
allogeneic bone marrow transplants. Bone Marrow Transplant 14:211–212, 1994. 49. Zannettino AC, Buhring HJ, Niutta S, et al: The sialomucin CD164 (MGC-24v) is an
20. Thomas E, Storb R, Clift RA, et al: Bone-marrow transplantation (first of two parts). adhesive glycoprotein expressed by human hematopoietic progenitors and bone mar-
N Engl J Med 292:832–843, 1975. row stromal cells that serves as a potent negative regulator of hematopoiesis. Blood
21. Hansen JA, Clift RA, Thomas ED, et al: Transplantation of marrow from an unrelated 92:2613–2628, 1998.
donor to a patient with acute leukemia. N Engl J Med 303:565–567, 1980. 50. Nilsson SK, Johnston HM, Whitty GA, et al: Osteopontin, a key component of the
22. O’Reilly RJ, Dupont B, Pahwa S, et al: Reconstitution in severe combined immunodefi- hematopoietic stem cell niche and regulator of primitive hematopoietic progenitor
ciency by transplantation of marrow from an unrelated donor. N Engl J Med 297:1311– cells. Blood 106:1232–1239, 2005.
1318, 1977. 51. Brunner S, Zaruba MM, Huber B, et al: Parathyroid hormone effectively induces mobi-
23. Appelbaum FR, Herzig GP, Ziegler JL, et al: Successful engraftment of cryopreserved lization of progenitor cells without depletion of bone marrow. Exp Hematol 36:1157–
autologous bone marrow in patients with malignant lymphoma. Blood 52:85–95, 1978. 1166, 2008.
24. Appelbaum FR, Deisseroth AB, Graw RG Jr, et al: Prolonged complete remission fol- 52. Ballen K, Mendizabal AM, Cutler C, et al: Phase II trial of parathyroid hormone after
lowing high dose chemotherapy of Burkitt’s lymphoma in relapse. Cancer 41:1059– double umbilical cord blood transplantation. Biol Blood Marrow Transplant 18:1851–
1063, 1978. 1858, 2012.
25. Center for International Blood & Marrow Transplant Research: Progress Report January- 53. Pulsipher MA, Chitphakdithai P, Logan BR, et al: Lower risk for serious adverse events
December 2013… Available at: http://www.cibmtr.org/About/ProceduresProgress/ and no increased risk for cancer after PBSC vs BM donation. Blood 123:3655–3663,
Documents/CIBMTR%20Progress%20Report%202013.pdf. 2014.
26. Weissman IL: Stem cells: Units of development, units of regeneration, and units in evo- 54. Styczynski J, Balduzzi A, Gil L, et al: Risk of complications during hematopoietic stem
lution. Cell 100:157–168, 2000. cell collection in pediatric sibling donors: A prospective European Group for Blood and
27. Spangrude GJ, Heimfeld S, Weissman IL: Purification and characterization of mouse Marrow Transplantation Pediatric Diseases Working Party study. Blood 119:2935–2942,
hematopoietic stem cells. Science 241:58–62, 1988. 2012.
28. Ikuta K, Weissman IL: Evidence that hematopoietic stem cells express mouse c-kit but 55. Chan KW, Gajewski JL, Supkis D Jr, et al: Use of minors as bone marrow donors:
do not depend on steel factor for their generation. Proc Natl Acad Sci U S A 89:1502– Current attitude and management. A survey of 56 pediatric transplantation centers.
1506, 1992. J Pediatr 128:644–648, 1996.
Kaushansky_chapter 23_p0353-0382.indd 374 9/19/15 12:47 AM

