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CHAPTER 11 VARIATIONS IN SHAPE AND DISTRIBUTION OF ERYTHROCYTES 99
SCHISTOCYTE
Schizocyte
A B
FIGURE 11–2A Schistocytes. FIGURE 11–2B Schistocytes.
C D
FIGURE 11–2C Bite cells. FIGURE 11–2D Blister cells.
COLOR: Red to salmon
SHAPE: Fragmented erythrocytes; many sizes and shapes may be present on a smear; often
display pointed extremities
Associated with: Microangiopathic hemolytic anemia (hemolytic uremic syndrome, thrombotic
thrombocytopenic purpura, disseminated intravascular coagulation), severe burns, renal graft
rejection
NOTE: Bite and blister cells are the result of splenic pitting of Heinz bodies (see Figure 12-5, B).
These cells are often included in the schistocyte category.
