Page 125 - Clinical Hematology Atlas

CHAPTER 11 VARIATIONS IN SHAPE AND DISTRIBUTION OF ERYTHROCYTES 109

ROULEAUX VERSUS AUTOAGGLUTINATION

A B
FIGURE 11–12A Rouleaux (3500). FIGURE 11–12B Rouleaux (31000).

ROULEAUX
DESCRIPTION: Erythrocytes arranged in rows like stacks of coins; increased proteins in patients
with rouleaux may make the background of the slide appear blue
Associated with: Acute and chronic inflammatory disorders, plasma cell myeloma,
lymphoplasmacytic lymphoma
NOTE: These aggregates will disperse with saline.

C D
FIGURE 11–12C Autoagglutination (3500). FIGURE 11–12D Autoagglutination (31000).
AUTOAGGLUTINATION

DESCRIPTION: Clumping of erythrocytes; outlines of individual cells may not be evident
Associated with: Antigen-antibody reactions
NOTE: Aggregate will not disperse with saline.