Page 66 - Clinical Hematology Atlas

50 SECTION TWO HEMATOPOIESIS

NEUTROPHILIC MYELOCYTE

A B
FIGURE 5–6A Neutrophilic myelocyte, early. FIGURE 5–6B Neutrophilic myelocyte, late.

Nucleus

Golgi

Cytoplasm
with primary
and secondary
C granules
FIGURE 5–6C Schematic of myelocyte, late.
D
FIGURE 5–6D Electron micrograph of myelocyte
(316,500).

SIZE: 12-18 mm
NUCLEUS: Round to oval; slightly eccentric; may have one flattened side; may be a clearing
next to the nucleus indicating the location of the Golgi
Nucleoli: Usually not visible
Chromatin: Coarse and more condensed than promyelocyte
CYTOPLASM: Slightly basophilic to cream-colored
Granules:
Primary: Few to moderate
Secondary: Variable number; they become predominant as cell matures
N/C RATIO: 2:1
REFERENCE INTERVAL:
Bone Marrow: 5% to 19%
Peripheral Blood: 0%
NOTE: Secondary granules in neutrophils are too small to resolve at the light microscope level.
They give the cytoplasm a grainy or sandy appearance, and the overall color is lavender to
pink. (See Figure 7-2 for eosinophilic myelocyte.)