Page 368 - ANUAL REPORT MOH 2017

3. Consultative services
4. Scientific and Technical training programmes

RESEARCH ACTIVITY
In 2017, research and medical officers of the Institute were engaged in 76 research projects. The Institute
published 96 scientific papers. In addition, staff of the Institute was involved in 179 presentations at
local and international conferences and other such events.
The following table lists the research projects conducted at the IMR in 2017:

Table 26
IMR Research Projects 2017
No Project Title
1. Population Pharmacokinetics-Pharmacodynamics (PKPD) of Colistin in Critically Ill Patients
with Multi Drug Resistant Gram-Negative Bacterial Infection: A Malaysian Scenario
2. Identification and Characterization of Potential Oncogenes and Tumour Suppressor Genes
Involved in the Pathogenesis of Oligodendroglioma and Glioblastoma Multiforme Using Next
Generation Sequencing
3. Differentiation of Hibiscus sabdariffa L. (Roselle) Anthocyanin Rich Extract by a Multi Step
Infrared Macro-Fingerprint Method for Anti-Obesity Derived Product
4. Bioavailability of Hibiscus sabdariffa L. (Roselle) in Rats: In Preparation of Tisane as Anti-
Obesity
5. Analysis of Specific Extracellular MicroRNA for Mesenchymal Stem Cell Modification in Liver
Cirrhosis
6. Identification of Novel Biomarkers in B-Cell Lymphoma
7. Proteomic Marker of Pyrethroid Resistance in Aedes (Stegomyia) aegypti (Linneaus) as a
Novel Tool in Resistance Detection and Management
8. Characterization of the Prevailing Sarcocystis Species in Environmental Samples of a
Recreational Island: A Preliminary Study
9. Determination of Antimicrobial Activity of Forensic Fly Larvae via Resazurin-Based
Turbidometric Assay
10. Transcriptomic Analysis of Burkholderia pseudomallei Isolated from Human and Environment
Using RNA Sequencing
11 Gene Expression and Immunomodulatory Studies on Samples from Dengue Virus Infected
Mice Treated with Carica papaya Leaf Juice (CPLJ) and Carica papaya Leaf Juice (CPLJ)
Freeze Dried Preparation
12. Sterile Insect Techniques for Dengue Vector Control
13. Outdoor Residual Spraying for the Control Simian Malaria in Sabah

14. Zika Virus in Vector Mosquitoes at Selected Sites in Malaysia: Preparedness for Control and
Prevention
15. Orthosiphon stamineus as a Potential Anti-Diabetic Drug in Gestational Diabetes Mellitus
16. The Effect of Carica papaya Leave Juice (Fresh Juice and Freeze-Dried Preparations) on the
Vascular Permeability Level of Dengue Virus Infected AG129 Mice
17. Epigenetic Studies of Type 2 Diabetes and Diabetic Nephropathy in Malaysian Population

MINISTRY OF HEALTH MALAYSIA ANNUAL REPORT 2017 367