Page 7 - Drug Discovery and Development: Prospects and Challenges
P. 7
Contents
Summary vii
Introduction 1
Natural Medicines According to Islamic and Old Malay
Scriptures 3
Progress in Pharmaceutical Development 5
Source of Drugs 7
Journey in Research: A Personal Experience 9
Isolation and Characterisation Studies 9
In Vitro and In Vivo Studies 13
Anti-cancer/Cytotoxicity 14
Anti-hyperglycemic 15
Anti-obesity 19
Wound Healing 20
Drug Development Process 21
Importance of Animal Study 22
Drug Formulation 23
The Miracle Plant, Centella asiatica 27
Introduction of C. asiatica 27
Wound Healing Process 29
Hydrogel 30
Development of Pegaga Research: From Laboratory to Serum X 31
Hydrogel Formulation using C asiatica 31
Pegaga Extraction 32
Optimisation of Fractionation 32
HPLC Analysis 34
Upscale Production of Pegaga Hydrogel 35

