Page 5 - Venu Teaching

History of Genetic Engineering

Isolation of DNA ligase
1967
st
1 Restriction Enzyme
1972 Using DNA cutting properties of
1973 restriction enzymes and ability of

ligase to join DNA molecule 1
st
recombinant DNA molecule
generated at Stanford University

1 self replicating recombinant
st
DNA molecule
(plasmid pSC101+foreign DNA)

Shaded area represent the period of major developments in each branch GMO’s

5 07/07/17 BSC 597 Genetic Engineering, Venu Cheriyath