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Primary and secondary immune response







              Primary immune response                                                                                         Secondary immune response


              first exposure –lag phase no

              antibody is produce                                                                                             -memory B cell recognize the same
                                                                                                                              antigen faster
              -takes 3 to 6 days for antibody to

              increase                                                                                                        -memory B cell proliferate and
                                                                                                                              differentiate rapidly into plasma cell to
              -because B cell takes time to

              proliferate and differentiate into                                                                              produce antibody
              plasma cell and memory B cell                                                                                   -the response is faster, concentration


              -low concentration of antibodies                                                                                antibodies is higher
              are produce, mainly IgM is

              produced                                                                                                        -Antibody produce mainly IgG

              - Antibodies increases and reach                                                                                -memory B cell able to recognize

              peak in ~10 days before declining                                                                               antigen for longer period of  time/
                                                                                                                              long lasting
              -the response is short lived
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