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SLEEP










          5 The combined therapy effectively returned                well during the day, despite the sleeping
          the insomniacs’ performances on the tasks to               difficulties.”
          normal levels. Those who received it became                   Dr Altena’s group has found that insomniacs’
          significantly slower on the simple task and                brains are structurally different to those of
          faster on the complex task when tested later.              good sleepers. They used a brain-scanning

          This outcome suggests that an insomniac’s brain            technique called voxel-based morphometry to
          works differently to others and that some of the           measure and compare the volumes of various
          cognitive changes associated with insomnia                 brain structures in 24 chronic insomniacs and
          are at least partly reversible.                            13 healthy control subjects. The insomniacs
             In  another  study,  Dr                                                      showed reduced volume of
          Altena and her colleagues              “Insomniacs                              grey matter in three regions
          found  that  insomniacs                                                         of  their  brains.  Plus,  the
          outperform good sleepers               suffer from a                            reduced volume of the orbito-
          on a verbal fluency task.                                                       frontal cortex was strongly
          Test subjects had to press          condition that’s                            related to the severity of the
          a button whenever a word                                                        insomnia – the more severe
          belonging to a specified             best described                             a volunteer’s complaints, the
          category  was  presented.                                                       greater the volume reduction.
          The performances of the              as a light form                              The results fit well with the
          insomniacs who received                                                         functions of the orbito-frontal
          sleep therapy for six weeks                 of stress”                          cortex, which is known to be
          was comparable to that of                                                       involved in decision-making
                                                                                                                                Scientific studies are trying
          the healthy control subjects                                                    and problem-solving, both             to get to the bottom of
          when they were tested again.                               of which are significantly impaired following              what makes for a good
                                                                                                                                night’s sleep
            “Insomniacs suffer from a physiological                  sleep deprivation. But it’s unclear whether
          condition best described as a light form of                these structural changes cause the insomnia
          stress, which can be measured in higher                    or come after it.
          brain activation when trying to fall asleep,”                “To  draw  conclusions  about  the  neural
          Dr Altena explains. “This hyper-arousal may                mechanisms underlying insomnia we need
          underlie some of the high-performance levels               to investigate which of these effects contribute

          we observed. It may serve as a compensatory                to the condition and which are consequences
          mechanism of the brain to function relatively              of it,” says Dr Altena.




          SLEEP AND MEMORY



          Don’t forget: beauty sleep is crucial

          Quintilian, a famous first-century    occur during short-wave sleep are
          Roman teacher of rhetoric, noted the   thought to mark the integration of
          “curious fact that the interval of a   new information with pre-existing
          single night will greatly increase the   knowledge. Also, changes in the
          strength of memory”. And it’s now     pattern of how genes are switched
          well established that sleep enhances   on or off during REM sleep may
          memory consolidation.                 promote the strengthening of
             Researchers from the University    neuronal connectivity that is thought
          of Haifa in Jordan have shown that a   to underlie memory formation.
          daytime nap enhances memory             One study found that sleep
          recall, and that even a short nap     deprivation promotes the generation
          lasting just six minutes is sufficient    of false memories. So using it as a
          to aid the processing of memories.    technique when interrogating
          The slow brainwave oscillations that   suspects seems fairly pointless.




          82  BBC SCIENCE FOCUS MAGAZINE COLLECTION
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