Page 48 - EatingWell Special Edition Superfoods 2019
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Y O U R  H E A L T H I E S T  M E A L T I M E










                        Research on the gut microbiome has exploded  (vegetarian,               vegan,   etc.),  those  who   ate  more
                     over the past decade. This frontier may just pro-          than   30   different   plant  types   per   week   had
                     vide the string theory of all human disease. “Name         gut microbiomes that were more diverse than
                     just about any ailment plaguing us and you’ll find   participants who ate 10 or fewer types of plants
                     some  researchers discovering the microbial angle  per week.
                     for a connection,” says Leach, whose latest book,              “The human microbiome is complex, but the

                     Rewild, came out in 2015. Recent studies have im-          more samples we get, the sooner we will be able
                     plicated gut microbes in everything from autism  to unravel the many ways the microbiome is as-
                     and depression to cancer and diabetes to heart  sociated with various health and disease states,”
                     disease and obesity. “It’s a water shed  moment for  said Knight after the release of the results. “The
                     human health,” says Leach.                                 American Gut Project is dynamic, with samples
                        He should know. Leach—with his frenetic en-             arriving from around the world daily. The anal-
                     ergy, powerful charisma and uncanny ability to  ysis             presented    in  this  paper  represents    a  sin-

                     step back and connect diverse dots—is one of the  gle snapshot, but we want eventually to go be-
                     most visible leaders of the gut-health movement.  yond making maps of the microbiome to making
                     In 2012, Leach founded the Human Food Project,  a micro biome GPS that tells you not just where
                     a global effort to study how diet affects the mi-          you are on that map, but where you want to go
                     crobial world within us.                                   and what to do in order to get there in terms of
                                                A  major    arm   of  that  is  diet, lifestyle or medications.”
                                             the   American      Gut   Proj-
           Numerous                          ect, thought to be the larg-       Building the Microbiome
           studies have                      est  microbiome     project   in   Until the moment we are born, we are still 100%
           shown that                        the  world,   co-led   by  Rob     human.    In  other  words,   bacteria-free.   Most   of
           scrubbing away                    Knight,    Ph.D.,   a  profes-     us  get  our  first  dose  of  microbes  while   travel-
           our microbes                      sor   at  the  University     of   ing through the birth canal. The second big dose

           may be                              Colorado’s  BioFrontiers  comes from breast milk. As babies grow, they pick
           weakening                         Institute    and   a  Howard       up critters from dirt, pets, family members and
           our bodies’                       Hughes     Medical    Institute    friends. By age 3, the microbiome has pretty much
           natural defenses.                 Early  Career  Scientist. The  set up camp.

                                             goal  is  to  map   the  diver-        But changing lifestyles are chipping away at
                                             sity of the  human gut—and  that microbiome. Early studies indicate that chil-
                     tease out patterns shaped by diet, age and life-           dren born by C-section—which reduces the mi-
                     style to  understand the factors most important  crobes an infant is first exposed to—have a higher
                     for a healthy gut microbiome.                              risk of celiac disease, obesity and type 1 diabe-
                        In 2018 the results from more than 10,000 peo-          tes. Add to that decreased breastfeeding and “our
                     ple who had signed up for the gut project were  overzealous use of antibiotics,” says Leach, who
                     published. After completing a questionnaire and  compares what antibiotics do to the gut micro-

                     a seven-day food journal and paying $99, partici-          biome to clear-cutting a forest.
                     pants sent a fecal sample to be analyzed. Some of              From   birth  to  age  5,  children  receive   more
                     the questions seemed odd: How many different               anti biotics  than  during   any  other   five-year  pe-
                     plants do you eat in a week? Born by C-section?  riod in their lives. One of Leach’s colleagues, New
                     Own a pet? Used an anti biotic in the past month?  York           University    microbiologist    Martin    Blaser,
                     But Leach explains that all of these things affect         M.D.,   believes  antibiotics   have   “deranged”    the
                     your microbiome.                                           micro  biome—even       causing   some   species   to  go

                        One of the most exciting findings showed that           extinct—and      that  their  overuse    is  why  many
                     a greater variety in plant-based foods in one’s            health problems, including type 1 diabetes, obe-
                     diet meant a greater diversity of micro biomes  sity and allergies, are on the rise.
                     in their gut. No matter the diet they followed                 Numerous studies have shown that  scrubbing





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