Page 86 - R2017 Final_BE Biomedical Curriculum and Syllabus - REC

Department of BME, REC

• To appreciate the emerging role of nanotechnology in society, the regulatory framework within
which it operates and the ethical issues it raises

UNIT INTRODUCTION 8
Scientific revolutions –Time and length scale in structures – Definition of a nanosystem –
Dimensionality and size dependent phenomena – Surface to volume ratio. Properties at nanoscale
(optical, mechanical, electronic, and magnetic). Definition, Objective and goal of Nanotechnology,
Importance of Nanoscale, revolution of Nanotechnology.

UNIT II GENERAL METHODS OF SYNTHESIS 12
Nanoparticles through homogeneous and heterogeneous nucleation-Growth controlled by surface
and diffusion process- Oswald ripening process - influence of reducing agents.
Fabrication methods – Top down processes: Milling, lithographics, Machining process, vapor
deposition. Bottom–Up process: Colloidal and Sol – gel methods, electro deposition, Self
Assembly

UNIT III NANOMATERIALS 9
Classification based on dimensionality- Quantum Dots, Wells and Wires- Carbon- based nano
materials (buckyballs, nanotubes, graphene)– Metalbased nano materials (nanogold, nanosilver
and metal oxides) -Nanocomposites- Nanopolymers – Nanoglasses –Nano ceramics -Biological
nanomaterials.

UNIT IV EXPERIMENTAL TECHNIQUES 9
Characterization – X- ray diffraction (XRD), Scanning Electron Microscopy, Transmission Electron
Microscope, Atomic force microscopy, Scanning Tunneling microscopy (STM), Scanning probe
microscopy (SPM), Optical and Raman spectroscopy.

UNIT V NANOTECHNOLOGY IN HEALTH CARE 7
Properties of nanocarriers; drug delivery systems used in nanomedicine; Enhanced Permeability
and Retention effect; Blood-brain barrier; Active and passive targeting of diseased cells;
Nanotechnology in defense - environmental application, Health and environmental impacts of
nanotechnology.
TOTAL: 45 PERIODS

OUTCOMES:
On completion of the course students will be able to
• Thorough knowledge of the general principles of physics, chemistry, electronics and biology
that play a role on the nanometer scale
• Understanding the essential concepts used in nanotechnology, synthesis and fabrication
• Understanding of materials and their properties at the atomic and nanometer level,
including an understanding of the intimate relationship between material scale
(nanostructure) and the properties/functionality of materials
• Having a sound grounding knowledge in the characterization techniques
• Demonstrate the socioeconomic impact of nanotechnology and ethical issues associated
with it.

TEXT BOOKS:
1. Edelstein. A.S. and R.C. Cammearata, eds., “Nanomaterials: Synthesis,
Properties and Applications”, Institute of Physics Publishing, Bristol and Philadelphia,
1996.
2. John Dinardo. N, “Nanoscale charecterisation of surfaces & Interfaces”, 2nd edition,
Weinheim Cambridge, Wiley-VCH, 2000

Curriculum and Syllabus | B.E Biomedical Engineering | R 2017 Page 86