Page 30 - M.E. Medical Electronics Curriculum and Syllabus - R2019

Department of BME, REC

PROFESSIONAL ELECTIVE II

MX19P21 BIOFLUID MECHANICS L T P C

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OBJECTIVES
• To get a thorough knowledge about the basic fluid mechanics concepts essential for
analyzing the biofluids.
• To understand the flow mechanics of different circulatory systems.
• To gain a thorough knowledge on devices used for measurement of flow of fluids

UNIT I INTRODUCTION 9
Newton’s laws, Stress, Strain, Elasticity, Hooks-law, viscosity, Newtonian fluid, Non-
Newtonian fluid, Viscoelastic fluids, vascular tree, Relationship between diameter, velocity
and pressure of blood flow, Resistance against flow.
Viscoelasticity - Viscoelastic models, Maxwell, Voigt and Kelvin Models, Response to
Harmonic variation, Use of viscoelastic models, Bio-Viscoelastic fluids: Protoplasm, Mucus,
Saliva, Synovial fluids.

UNIT II FLOW PROPERTIES 9
Intrinsic Fluid Properties, Hydrostatics, Macroscopic Balances of Mass and Momentum,
Microscopic Balances of Mass and Momentum, Bernoulli Equation, Dimensional
Analysis. Fluid Mechanics in a Straight Tube, Boundary Layer Separation.
Physical, Chemical and Rheological properties of blood. Fahraeus -Lindquist effect and
inverse effect, distribution of suspended particles in a narrow rigid tube. Nature of red blood
cells in tightly fitting tubes, hematocrit in very narrow tube.

UNIT III CARDIOVASCULAR MECHANICS 9
Cardiovascular system. Mechanical properties of blood vessels, Analysis of Thin-Walled
Cylindrical Tubes. Analysis of Thick-Walled Cylindrical Tubes. Systemic Circulation,
Coronary Circulation, Cerebral and Renal Circulations, Microcirculation. Windkessel
Models for the Human Circulation, Continuum Models for Pulsatile Flow
Dynamics, Hemodynamic Assessment of Prosthetic Heart Valves

UNIT IV RESPIRATORY MECHANICS 9
Alveoli mechanics, Gas Exchange in the Lungs, Interaction of Blood and Lung P-V curve of
Lung, Pulmonary Circulation, Flow in Collapsible Vessels. Airway resistance, Physics of
Lung diseases.

UNIT V FLOW MEASURING DEVICES 9
Flow measuring and monitoring systems manometers, orifice meter, venture meter and
rotameter Measurement of viscosity using extrusion rheometer, plate and cone viscometer,
coaxial cylinder viscometer

TOTAL: 45 PERIODS
OUTCOMES:
On completion of the course the students will be able to
• Understand the fundamentals of fluid mechanics.
• Explain the physical and rheological properties of biofluids.
• Describe the circulatory mechanics associated with prosthetic heart valves.

R 2019 - Curriculum and Syllabus/ M.E Medical Electronics Page 30