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30          SECTION II    HIGH-YIELD GENERAL PRINCIPLES                                                                                                                         HIGH-YIELD GENERAL PRINCIPLES




                                                    ` `HOW TO USE THE DATABASE


                                                   The 2020 edition of First Aid for the USMLE Step 1 contains a revised and
                                                   expanded database of basic science material that students, student authors,
                                                   and faculty authors have identified as high yield for board review. The
                                                   information is presented in a partially organ-based format. Hence, Section
                                                   II is devoted to the foundational principles of biochemistry, microbiology,
                                                   immunology, basic pathology, basic pharmacology, and public health
                                                   sciences. Section III focuses on organ systems, with subsections covering
                                                   the embryology, anatomy and histology, physiology, clinical pathology, and
                                                   clinical pharmacology relevant to each. Each subsection is then divided
                                                   into smaller topic areas containing related facts. Individual facts are
                                                   generally presented in a three-column format, with the Title of the fact in
                                                   the first column, the Description of the fact in the second column, and the
                                                   Mnemonic or Special Note in the third column. Some facts do not have a
                                                   mnemonic and are presented in a two-column format. Others are presented
                                                   in list or tabular form in order to emphasize key associations.

                                                   The  database  structure  used  in Sections II  and III  is useful  for  reviewing
                                                   material already learned. These sections are not ideal for learning complex
                                                   or highly conceptual material for the first time.

                                                   The database of high-yield facts is not comprehensive. Use it to complement
                                                   your core study mate  rial and not as your primary study source. The facts and
                                                   notes have been condensed and edited to emphasize the essential material,
                                                   and as a result, each entry is “incomplete” and arguably “over-simplified.”
                                                   Often, the more you research a topic, the more complex it becomes, with
                                                   certain topics resisting simplification. Work with the material, add your own
                                                   notes and mnemonics, and recognize that not all memory techniques work
                                                   for all students.
                                                   We update the database of high-yield facts annually to keep current with
                                                   new trends in boards emphasis, including clinical relevance. However, we
                                                   must note that inevitably many other high-yield topics are not yet included
                                                   in our database.

                                                   We actively encourage medical students and faculty to submit high-yield
                                                   topics, well-written entries, diagrams, clinical images, and useful mnemonics
                                                   so that we may enhance the database for future students. We also solicit
                                                   recommendations of alternate tools for study that may be useful in preparing
                                                   for the examination, such as charts, flash cards, apps, and online resources
                                                   (see How to Contribute, p. xix).






















          FAS1_2019_01-Biochem.indd   30                                                                                11/7/19   3:16 PM
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