Page 194 - pathology_services_handbook_5th_edition_2018

4.3 Guidelines for Full Blood Picture request:

Full blood picture are indicated in cases as below:
HTAA, KUANTAN a. History and clinical findings of:

• thrombocytopenia (petechial rash, easy bruising)
• neutropenia
• symptomatic anaemia
b. Suspicion of haematological malignancy e.g. acute/ chronic leukemias, MPN,
MDS, LPD based on:-
• Symptoms e.g . weight loss, fever/ PUO, itching, easy bruising,
hyperviscosity syndrome
• Clinical findings: lymphadenopathy, splenomegaly, hepatomegaly, plethora,
petechia.
c. Suspicion of disseminated non-haematological malignancy
d. Clinical suspicion of:
• Haemolysis
• MAHA/ fragmentation syndrome supported by relevant biochemical,
coagulation and hematological investigation results (e.g. serum bilirubin,
reticulo cyte count, LDH, DCT, PT, APTT etc.)
e. Infection/ inflammatory condition that may require FBP to confirm or support
diagnosis e.g. infectious monucleosis, parasitic disease (malaria).
f. Clinical suspicion of thalassemia/ hemoglobinopathy or membrane disorder
g. When performing bone marrow aspirates procedure.
h. Abnormal blood cell indices :
WBC > 30 x 109/L , WBC < 3 x 109/L .
Abnormality of the differential WBC:
Neutrophils: < 1.0 x 109/L, > 20 x 109/L
Lymphocytes: > 5 x 109/L
Monocytes: > 1.5 x 109/L
Eosinophils > 1.5 x 109/L
Platelets count < 100 x 109/L or Platelet > 1000 x 109/L.
Hb < 8 g/dL (ISLH: 7), Hb: > 18g/dl (male), 16.5g/dl (female).
MCV < 75fl, MCV > 100 fl

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