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4          Genesis Growth And Future of Cardiodiabetic Medicine




          Metabolic Medicine                                 CAD in Diabetics is not only frequent and occurs at a
                                                             younger age and women and the involvement is also
          Metabolic Medicine is a sub-specialty within Internal
          medicine which  can  be defined as a group  of     more extensive.  Triple  vessel  disease  and  left main
          overlapping  areas  of clinical  practice with  common   stem lesion are more common. Intramural arteries are
          dependence  on detailed  understanding of  basic   also  involved producing,  coronary  microangiopathy.

          biochemistry  and metabolism.    It therefore  falls   Silent myocardial  ischemia  and  silent  infarcts  are
          within  the areas  of expertise  of both the physician   more common. Pump failure, cardiogenic shock and
          and chemical pathologist.                          reinfarction  following  acute myocardial infarction
                                                             (AMI) are distinctly higher in diabetes. Diabetic state
          Metabolic Syndrome                                 does not come in way of providing benefit by catheter
                                                             interventions or by bypass surgery but the necessity
          The metabolic syndrome may be more useful when     of a repeat procedure is higher in the long run.
          considering prevention of the continuum from obesity
          through diabetes to cardiovascular disease, whereas   DC is another manifestation of cardiac involvement.
          the term cardiodiabetes is  more  applicable  to the   It is a consequence  of involvement  of intramural
          particular spectrum of cardiovascular disease,  plus   arteries  without  affection  of epicardial  coronary
          more diffuse peripheral  vascular  and  renal disease,   arteries, but it also has extravascular component like
          that is associated with diabetes.                  interstitial fibrosis and metabolic control of diabetes
                                                             also  play  an important part.  In  individuals after  35-
          Diabetologists, cardiologists,  lipidologists  and  renal   40 years, CAD may closely mimic DC and coronary
          physicians  joint specialist  clinics run at hospital   angiography  is  necessary  to  discriminate between
          centres, Primary Care Trust (PCT) one-stop clinics.  them.  On  occasions  both  may co-exist in the same
                                                             patients.
          Life Style Medicine                                Sudden cardiac death  (SCD) is the most dreadful
          Lifestyle  medicine is a scientific  approach to   complication and it is 1.8 times more common in men
          decreasing disease risk and illness burden by utilizing   and  3 times  common is  women compared  to non-
          lifestyle  interventions such as nutrition,  physical   Diabetics.  CAD, DC and autonomic  cardiovascular
          activity,  stress  reduction, rest, smoking  cessation,   neuropathy contribute to it. The  availability of
          and  avoidance  of alcohol  abuse. Lifestyle  medicine   powerful  antiarrhythmic drugs  like  Amiodarone  and
          is  the recommended foundational  approach to      Automatic  implantable cardiovertor  defibrillator  has
          preventing and treating many chronic diseases.
                                                             greatly improved the prospects of survival.
          Concept Note                                       Recognition of Hypertension in Diabetics is
          Cardio-Diabetology  is  fast emerging  as a sub-   of crucial importance because -
          speciality throughout the globe to tackle the menace
          of cardiac related mortality in Diabetes, particularly   1.It is a major risk factor for development and progress
          NIDDM.                                             of diabetic microangiopathy.
                                                             2.It is also a greater risk factor for the development
          Cardiac involvement in Diabetes commonly manifests   of  macrovascular  disease  in a diabetic than  in
          as coronary artery disease (CAD) and less commonly   nondiabetics.
          as dilated cardiomyopathy (DC)  and autonomic
          cardiovascular neuropathy. CAD alone accounts, for   3.Diabetics  with hypertension  are  prone  for
          the major chunk of mortality in diabetes.          development of coronary heart disease.  especially
                                                             when there is associated left ventricular hypertrophy
          CAD is the leading cause of mortality in Diabetics. It
          not only involves the epicardial coronary arteries but
          also the intramural coronary arteries. Silent ischemic
          events constitute a special feature of presentation.

          CAD in Diabetics is  multifactorial but dyslipidemia
          has a major impact on it. The lipid profile in Indian’s
          is  different  compared  to the West and comprises
          of normal or near normal total cholesterol and  LDL
          cholesterol  with raised  triglycerides  and low HDL
          cholesterol.



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