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Cardio Diabetes Medicine 2017 7

Mortality in DM with CAD: from endothelial cells (EC) in the late stages of
atherosclerosis.
Mortality was twice as high in Diabetic Patients
(35.9% versus 17 9%) influence of Diabetes Mellitus
on heart failure risk and outcome Christophe Bauters Cardio Diabetology growth in india :
corresponding author1 Nicolas Lamblin,1 Eugéne Prof. Sam G P Moses, Chennai formed the
P Mc Fadden,1 Eric Van Belle,1 Alain Millaire,1 Cardiodiabetology study group in 1988 along with
and Pascal de roote1Cardiovasc Diabetol. 2013;2: 1. Prof.Dr.Anantha subramaniam & Dr.J.K.Ramanakumar
-On 28 July 1988 – API HYD Chapter & DAI Southern
th
Pathogenic Link between Diabetes and Chapter National Seminar on Cardio Diabetology –
Cardiovascular disease Prof.BK Sahay Hyderabad – President
Type 2 Diabetes and Cardiovascular diseases could be -In 1988, Dr.J.K Ramanakumar, Chennai – Actively
considered different aspects of the same syndrome: Conducted the Cardiodiabetology Meetings
i.e. the metabolic syndrome. Metabolic syndrome
is a cluster of metabolic abnormalities which -In 1991 – Prof.Dr.Sam GP Moses Brought out the First
includes obesity, insulin resistance, dyslipidemia, Cardiodiabetology Book and Presented a Copy to
hypertension, endothelial dysfunction. Endothelial Prof.Dr.S.Arulrhaj.
dysfunction, which represents a common trait of -1998 – PC Manoria Past President API – APICON – PG
the type 2 diabetes and cardiovascular diseases, is Medicine. Cardio Diabetology, Book Published
characterized by a reduction of the bioavailability of
vasodilators, mainly nitric oxide, which causes an History Of Cardio Diabetology Journal
impairment of endothelium-dependent vasodilation. Cardiovascular Diabetology is a peer-reviewed open
Endothelium-derived nitric oxide is a potent access medical journal covering the intersection
endogenous vasodilator that plays a major role in of cardiology and diabetology, meaning the
vascular tone; it is synthesized by endothelial nitric connection between diabetes, metabolic syndrome
oxide synthase in a multistep reaction from L-arginine. and cardiovascular diseases. It is published by
Genetic variants on eNOS gene are associated to type BioMed Central and was established in 2002, with
2 diabetes, cardiovascular diseases and metabolic Enrique Fisman (Tel-Aviv University) and Alexander
syndrome. Tenenbaum (Sheba Medical Center) as founding
In 2015 we completed a 9 year follow-up in subjects editors-in-chief. A printed version is periodically
1
treated for 18 months with L-arginine orally . It has distributed in India by Panacea Biotec Ltd.
been estimated that it is possible to maintain a better The journal is abstracted and indexed in Current
sensitivity and insulin secretion, while complying with Contents, EMBASE, MEDLINE/PubMed, Science
a type 2 diabetes reduced the incidence in treated Citation Index, and Scopus. According to the Journal
subjects. The result seems to demonstrate the Citation Reports, the journal has a 2016 impact factor
ability of L-arginine to induce a positive metabolic of 4.752. [1]
memory capable of delaying the onset of diabetes
mellitus. Moreover, the presence of a greater number Cardio Diabetes Medicine Today
of progenitor endothelial cells, the reduction in
markers of oxidative stress also seems to indicate Cardiometabolic Medicine Foundation, UK founded
the presence of a vascular memory. As vascular by a Respected throughout leader in metabolic
memory can affect the metabolic memory will be the medicine
aim of future in vitro and in vivo studies in human The Cardiometabolic Medicine Foundation will
endothelial cell line and in progenitor cells. provide a resource for patients and healthcare
profesionas who wish to pursue and individualized
These findings, together with the
Hyperhomocysteinemia reported in diabetic and comprehensive approach to the prevention and
patients, strongly suggest that homocysteine might management of common vascular and metabolic
be considered a risk factor in the development of disorders including heart diseases, stroke, diabetes
cardiovascular complications associated to type 2 and dementia.
Diabetes mellitus. The Foundation encourages an evidence –based
Subendothelial accumulation of extracellular lipids approach to cardiometabolic disease.
leads to the formation of foam cells primarily Cutting edge clinical science will be integrated with
derived from monocytes/ macrophages, but also emerging complementary therapies to move beyond

Cardio Diabetes Medicine