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ceived as a sign of prosperity rather than a negative to improved ethnic-specific clinical practice both
impact on health in some cultures. Hence, the impact for migrant and indigenous groups of affected
of PCOS on psychological issues based on the ethnic women; this takes into account sociocultural is-
background must be taken into account. sues that vary based on one’s ethnic background.
10. A greater awareness of this aspect among clini-
Summary & Conclusion cians practicing in different settings with varying
1. Central obesity rather than BMI (based on stan- resources would enhance the quality of care and
dard cutoff of 30 kg/m ) affects the metabolic a more holistic approach to managing PCOS in
2
issues of PCOS in Asians; thus the need to mea- women by adopting a life-cycle approach to the
sure waist circumference rather than BMI alone. problem.
2. South Asians presenting with anovular PCOS
were significantly younger, had more severe hir- References
suitism and a higher prevalence of acanthosis 1. Hart R, Hickey M, Franks S. Definitions, prevalence and symptoms of
nigricans than their Caucasian counterparts. Polycystic ovaries and Polycystic ovary syndrome. Best Pract Res Clin Ob-
stet Gynaecol. 2004;18:671–683. doi: 10.1016/j.bpobgyn.2004.05.001.
3. The chief clinical features of PCOS – reproductive 2. Homberg R. What is polycystic ovarian syndrome? - A proposal for a
and hyperandrogenic effects – are closely inter- consensus on the definition and diagnosis of polycystic ovarian syndrome.
woven with the insulin resistance that is its cen- Hum Reprod. 2002;17:2495–2499. doi: 10.1093/humrep/17.10.2495.]
tral metabolic problem. The clinical heterogeneity 3. Balen A, Michelmore K. What is polycystic ovary syndrome? Are nation-
of its presentation has led to much debate and al views important? Hum Reprod. 2002;17:2219–2227. doi: 10.1093/
deliberation on a more pragmatic approach to the humrep/17.9.2219.
diagnosis of PCOS. 4. Rotterdam ESHRE/ASRM-Sponsored PCOS consensus workshop group.
Revised 2003 consensus on diagnostic criteria and long-term health risks
4. In parallel, there is ethnic-based geographic vari- related to polycysticovary syndrome (PCOS) Hum Reprod. 2004;19:41–
ation in the prevalence, complications and out- 7. doi: 10.1093/humrep/deh098.
comes of the main metabolic problems of PCOS 5. Gambineri A, Pelusi C, Vicennati V, Pagotto U, Pasquali R. Obesity and the
and its inherent hyperinsulinemia, Type 2diabe- polycystic ovary syndrome. International Journal of Obesity and Related
tes mellitus and hypertension. Metabolic Disorders. 2002;26:883–896. doi: 10.1038/sj.ijo.0801994.
5. PCOS, an ill defined symptom complex needs
its due attention. As ethnicity plays an important
role in this symptom complex, there is a greater
need to know the characteristics of the same in
different populations.
6. Women presenting with oligomenorrhea should
be further investigated for PCOS and treated ac-
cordingly.
7. There are report of lower response to advance fer-
tility treatment among asian women with PCOS
that require further study to determine whether
this is due to lower ovarian volume or linked to
greater insulin resistance.
8. Overall occurrence of a single or couple of fea-
tures is less common as compared to that of
multiple characters. This is suggestive of a chain
of pathological and hormonal reactions. Timely
therapeutic intervention can halt this ongoing
process. Nevertheless, complaint related to a
single feature should not be neglected.
9. Knowledge on the etiology of PCOS will be fur-
ther improved by in-depth study of phenotypic
and genotypic differences of PCOS in specific
ethnic groups the world over. This in turn will lead
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