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Hypertension in Elderly Population                                  291





                 Bell of the stethoscope should be lightly applied over  Evaluation:
                 the  brachial  artery  for auscultation  because Korot-  FBS,PPBS,  lipid  profile,  complete blood  count,  uri-
                 koff  sounds are  low  pitched  (9).  BP  measurements   nalysis  with  microscopic examination,  and  electro-
                 are recorded to the nearest 2 mmHg. Three measure-  cardiogram are reasonable for an initial evaluation.
                 ments  should be done and  average  of the  last two
                 measurements should be taken as the value for that   Treatment Issues in Elderly
                 visit.  Three  visits with  six  measurements should be
                 taken to diagnose systemic hypertension .            - Antihypertensive  drugs  are strongly  advocated  in
                                                                      elderly  , though  most datas are  on patients with
                 White coat hypertension is more commonly seen in     age < 80 yrs .
                 elderly  –Home monitoring and  ABPM  have  got ad-
                 vantage in this population. Ambulatory (24 hour) BP     - HYVET  trial demonstrated  clear benefit if used
                 monitoring can detect dipper, non-dipper, early morn-  above age > 80 yrs of age.
                 ing surge pattern-which is associated with severe CV
                 events.                                            Goal to be achieved :
                                                                    Below 80 yr target BP 140/80 is desirable , but above
                 Clinical Issues                                    80 yr, SBP 140-45 is desirable.
                 •   White Coat Hypertension                        In elderly BP lowering below 130/ 70 mm Hg not de-
                 •   Labile Hypertension                            sirable due to increased incidence of orthostatic fall.

                 •   Pseudo hypertension                            As per JNC 8,
                 •   Postural hypotension                           “In the general  population aged  60 years  or  older,
                                                                    initiate pharmacologic treatment to lower BP at sys-
                 •   Secondary Hypertension                         tolic blood pressure (SBP) of 150 mm Hg or higher or
                 •   Resistant hypertension                         diastolic blood pressure (DBP) of 90 mm Hg or higher
                                                                    and treat to a goal SBP lower than 150 mm Hg and
                 •   Polypharmacy and drug interaction              goal DBP lower than 90 mm Hg.
                 •   Nonadherence                                   (Recommendation : grade A)
                 Measuring only office BP may give erroneous result   In the general  population  aged  60 years  or  older,  if
                 in BP due to white  coat  hypertension.For  that  pur-  pharmacologic treatment for high BP results in low-
                 pose,24  Hrs  ABPM  should be considered.  There  is   er  achieved  SBP  (for example,  <140  mm  Hg)  and
                 Fluctuation in BP from day to day, hour to hour due to   treatment  is  not associated with  adverse  effects on
                 arterial stiffness and decreased windkessel effect of   health or quality of life, treatment does not need to
                 aorta. Higher prevalence of Atherosclerosis gives rise   be adjusted.
                 to a  substantial portion  of  patients with pseudo-hy-
                 pertension.  Loss  of autonomic  tones, baroreceptor   (Recommendation: grade E)”
                 sensitivity gives  rise  to postural  hypotension and
                 post prandial hyotension. After a high-carbohydrate  Treatment issues:
                 meal, supine  BP  declines, and heart rate increases
                 without an increase in plasma norepinephrine levels .  Non Pharmacological treatment:
                                                                    Lifestyle changes particularly weight loss, avoidance
                 Secondary hypertension should be suspected if there
                 is  sudden surge  of SBP  and DBP, particularly  DBP,   of  sedentary  lifestyle,  reduced  sodium intake  are
                 occurrence  of Malignant  hypertension,  presence  of   beneficial in controlling BP in elderly  hypertensive.
                 resistant hypertension.Common secondary causes of   However these changes have to be in moderation, as
                 hypertension  are  chronic  kidney disease,  reno-vas-  they should not compromise  with the quality-of-life
                 cular hypertension, Obstructive Sleep  Apnoea, Hy-  in the elderly  as  IHD,  cardiac failure,  renal  failure,
                 pothyroidism. Resistant Hypertension is seen due to   peripheral vascular disease and orthopedic problems
                 arterial stiffness, Higher baseline BP , Co-morbidities,   are also co-existent in this population.
                 increase salt intake, sedentary lifestyle, nicotine, al-
                 cohol  intake,Poor compliance,  Volume overload,   Pharmacological Treatment:
                 NSAID use.                                         What guidelines say
                                                                    As per ACC/AHA 2011 ,



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