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Cardio Diabetes Medicine 2017                                   467





                                     Nutrient  Manipulation  for Obesity


                                      Metabolic Syndrome and Diabetes






                                             Dr.Sethuramashankaran A, PGDD
                                                 Physician and Diabetologist, Chennai








                 Abstract:                                          genetic and  environmental  factors contribute  to the
                 Nutrition is essential to  maintain  optimal health.   development of obesity, metabolic syndrome and di-
                 When nutrition becomes inappropriate it causes over   abetes Their alarming rise in prevalence necessitates
                 weight and obesity  leading  to metabolic syndrome,   the  need to study the  modifiable factors and  novel
                 diabetes  and associated metabolic conditions like   treatment  options(11).  At an individual  level  causes
                 hypertension, dyslipidemia, etc. This article enumer-  of obesity  are  physical inactivity,  and  increased in-
                 ates the various factors that causes obesity, meta-  takes of foods high in saturated fats and sugars. At
                 bolic syndrome  and diabetes  with focus on energy   a societal level, non-supportive policies in the health,
                 imbalance and  weight  gain.  The  alarming  increase   agriculture, transport,  urban planning, environment,
                 in prevalence with 13% of the adult population being   food processing, distribution, marketing, and educa-
                 obese  and 39%  over  weight. Their  association with   tion sectors can all have influence. Obesity has been
                 more deaths  worldwide than  underweight necessi-  shown to increase the risks of chronic disease, such
                 tates the need  to address  the obesogenic  environ-  as  metabolic syndrome,  type  2 diabetes,  cardiovas-
                 ment  that  causes it. Diet rich  in carbohydrates, re-  cular disease, hypertension, stroke and certain types
                 fined sugars and fats along with sedentary life style   of cancer(1). To promote weight loss, changes in life
                 contribute to the obesogenic environment. Dietary   style affecting the dietary habits and physical activi-
                 strategies that  help in weight loss and  weight man-  ties are to be implemented.
                 agement were reviewed.  Certain type  of diets  were
                 found  to be superior  when  compared to others as   Facts:
                 they showed beneficial effects on                  Obesity is  one of the most common,  but  most ne-
                                                                    glected  public health  problem in the developed  and
                 cardiovascular and diabetes risk profiles.
                                                                    developing countries. In 2014,an estimated 1.9 billion
                                                                    adults aged 18 years and older were overweight, with
                 Key words:
                                                                    one third of these classified as obese. The worldwide
                 Obesity, metabolic syndrome, type 2 diabetes, carbo-  prevalence  of obesity  more  than  doubled between
                 hydrates, proteins, fats, dietary strategy, weight loss,   1980 and 2014. An estimated 41 million children under
                 weight maintenance, ad libitum.                    the age of 5 years were overweight or obese. Near-
                                                                    ly half of the children under 5 who were overweight
                 Introduction:                                      or obese in 2014 lived in Asia. Overweight and obe-
                 Body weight is an intricate balance between calories   sity  are  linked  to more  deaths worldwide  than  un-
                 consumed (energy intake) and calories burned (ener-  derweight.  Globally  there are  more  people  who are
                 gy expenditure). Body weight is gained when energy   obese  than  underweight except  sub-Saharan Africa
                 intake (nutrition) exceeds energy expenditure over an   and parts of Asia. United Nations General Assembly
                 extended period  of time leading  to overweight  and   on Prevention and Control of Non  Communicable
                 obesity. The exact cause whether it is the increased   Diseases of 2011 recognizes the importance of reduc-
                 energy  intake (nutrition)  or the  reduced energy  ex-  ing unhealthy diet and physical inactivity(1). Increase
                 penditure is not clearly known; it is a combination of   in obesity, abdominal  obesity, metabolic  syndrome
                 both in varying  proportions  in each individual. Both   in Asian Indians leads to diabetes and  atherogen-


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