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Cardio Diabetes Medicine 2017 531
Standard Approaches to Therapy Result in
Prolonged Exposure to Elevated Glucose
10% Diet/Exercise Sulfonylurea or Combination Insulin
Metformin Therapy
Monotherapy 9.6%
at Last 9% 8.6% 9.0%
MeanA1C Visit 8%
7%
ADA
Goal
<7%
6%
Diagnosis 2 3 4 5 6 7 8 9 10
Years
At insulin initiation, the average patient had:
■ 5 years with A1C >8%
■ 10 years with A1C >7%
Brown JB, et al. Diabetes Care.
2004;27:1535-1540.
Cardio Diabetes Medicine

