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Cardio Diabetes Medicine 2017 607

Indian SMS Study (2013) Cumulative incidence of diabetes (%) • First examples of a clinical outcome
using mobile technology and mobile
Control: 27.4
health in the field of prevention of T2D.
Intervention: 18.5
• Mobile phone messaging was found
Relative risk reduction (%) to be practical and affordable to deliver.
Intervention : 36.0 • Early improvement in glucose toler-
ance (NGT in 6 months) significantly
reduced the risk of development of di-
abetes. Persons who reverted to NGT
in the first 6 months had the highest
probability of remaining free of diabe-
tes at the end of 2 years. The RRR in
people who reverted to NGT was 75%
when compared with the remaining par-
ticipants.
• Development of Diabetes was asso-
ciated with deterioration in beta cell
function. Beta cell function showed
significant improvement in those who
reverted to NGT.
• Persons who had Hypertriglyceridemic
Waist Phenotype (HTWP), a combination
of elevated waist circumference (WC)
(> 90cms in men) and hyper triglyceri-
demia (fasting serum triglycerides > 150
mg/dl), had higher risk of developing
diabetes during the study period.

• Elevated levels of serum Retinol
binding protein-4 (RBP-4) and Gamma-
glutamyl Transferase (GGT) were also
useful predictors of incident diabetes.
Presence a HTWP can be used as a
biomarker for T2D.
• Beneficial effects of lifestyle interven-
tion were the result of increased compli-
ance to healthy diet principles advised,
independent of physical activity.

Diabetes Community Life- Cumulative incidence of diabetes (%) • Relative Risk Reduction varied by type
style Improvement Program of prediabetes.
Control: 34.9
(D-CLIP) (2016) • The reduction was higher in older peo-
Intervention: 25.7
ple, male or obese.
• 72% of the participants required met-
Relative risk reduction (%) formin for reducing the risk of diabetes.
Intervention : 32.0

Cardio Diabetes Medicine