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Chapter 3  CARE OF THE PATIENT WITH CRITICAL CARDIAC AND VASCULAR NEEDS        117




                               TABLE 3–7  Drugs That Affect Contractility (Continued)
                                                Action              Use             Precautions
                               Epinephrine      Synthetic form of   First-line drug   Continuous cardiac
                                                adrenaline that stim- in most       monitoring is
                                                ulates the action of   advanced car-  needed to see HR
                                                the sympathetic ner- diac life support  increases
                                                vous system         algorithms for   Given IV push in an
                                                Causes vasocon-     cardiac arrest   arrest. Infusion
                                                striction leading to   bradycardia and   may be prepared
                                                increased HR        <BP             via pump
                                                                    Also given when   Assess VS fre-
                                                                    patient is in   quently during ini-
                                                                    symptomatic     tiation and infusion
                                                                    bradycardias
                                                                    and heart       Destroyed in alka-
                                                                    blocks          line solutions like
                                                                                    bicarbonate; so
                                                                                    use separate line
                                                                                    for infusion
                                                                                    Check label as
                                                                                    comes in varying
                                                                                    solutions
                               Dobutrex (Dob-   Works on B1 and B2   In acute heart   Always use infu-              Downloaded by [ Faculty of Nursing, Chiangmai University 5.62.158.117] at [07/18/16]. Copyright © McGraw-Hill Global Education Holdings, LLC. Not to be redistributed or modified in any way without permission.
                               utamine)         receptors of adren-  failure        sion pump for
                                                ergic system to                     administration
                                                increase contractility              Assess VS fre-
                                                and reduce afterload                quently during ini-
                                                Improves CO                         tiation and during
                                                                                    infusion
                                                                                    Monitor SaO
                                                                                               2
                                                                                    Observe especially
                                                                                    for hypotension
                                                                                    and tachycardia
                               Milrinone        Phosphodiesterase   For acute heart   Always use an
                               (Primacor)       inhibitor           failure         infusion pump
                                                Increases contractil-               Assess VS fre-
                                                ity by blocking the                 quently during ini-
                                                breakdown of cyclic                 tiation and during
                                                AMP                                 infusion
                                                Also vasodilates and                Monitor SaO
                                                                                               2
                                                reduces afterload                   Observe especially
                                                                                    for hypotension,
                                                                                    ventricular dys-
                                                                                    rhythmias, and
                                                                                    tachycardia
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