Page 188 - Color_Atlas_of_Physiology_5th_Ed._-_A._Despopoulos_2003

A. H secretion
+
Lumen H - Blood H - +
ATPase (?)
+
ATPase H 2 O
H 2 O
H + H +
Na + H + H 2 O K + H + –
H + OH + CO 2
OH + CO 2 + CA II The Kidney and Acid–Base Balance I
–
NHE3 + +
carrier CA II H /K -ATPase Cl –
– –
HCO 3 HCO 3
– +
HCO 3 H
2 Type A intercalated cell
–
Na + HCO 3
Plate 7.14
H + hNBC
1 Proximal tubule cell
– H +
HCO 3
pH Cl – Na +
Filtrate: 7.4
Late proximal: 6.6 3 Type B intercalated cell
Urine,min.: 4.5
Urine, max.: 8.2

–
B. HCO 3 reabsorption
–
Blood
HCO 3
H +
H 2 O
Na +
H +
CA IV

+ OH –
CO 2 CO 2
+ II
H 2 O CA HCO 3 –
hNBC
Na + Filtrate: 100%
–
Lumen HCO 3 Late proximal: 10%
Urine: < 1%
Proximal
tubule cells HCO 3 –
175
Despopoulos, Color Atlas of Physiology © 2003 Thieme
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