Page 30 - Color Atlas Physiology
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A.  Ca  transport through the ER membrane
            2+
                      Nucleus
        1                             2
                               Cytosol

                                                    Ca 2+


                                                           2+
           2+
         Ca -ATPase      Endoplasmic  Signal             Ca  channel   Transport In, Through and Between Cells I
                         reticulum (ER)
                                      (depolarization,
                   Ca 2+                hormon, etc.)  Discharge
                  Storage
                 –5
                                                         –8
                        –8
               (10 )   10 mol/l  2+ Cytosolic   10 –5  (10 )mol/l
                                Ca  concentration
         B.  Mitochondrial transport
                                                                       Plate 1.8
                           Outer membrane
                            Inner membrane
                                 Matrix                 ATP synthetase
                                 Crista
                                  Inter-                Ribosomes
                              membranous
                                  space
                                                        Granules
                                 Cytosol
         1
                 +
         Formation of H  gradient     2
                                       +
                                      H  gradient driving ATP synthesis and carriers
                NADH + H +
                     NAD +      H 2 O                       Pyruvate –
                                      P i  + ADP 3–            etc.
                          +
                         2H + ½O 2          +
                                           H    synthetase  ADP 3–  P i
         Matrix                               ATP              Carrier
                                               ATP 4–
                 e –
                                                 a        b    c
         Enzyme complexes         H +
         of respiratory chain         H +  +        ATP   +   +
                                 H +     H               H   H
         Intermembranous        +     H +  +   ATP 4–
         space                 H         H            Ca 2+
                                      H +
         Cytoplasm
                         Porins                                      17
                                                                     17
       Despopoulos, Color Atlas of Physiology © 2003 Thieme
       All rights reserved. Usage subject to terms and conditions of license.
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