Page 32 - Color Atlas Physiology
P. 32

C.  Gap junction

                              Cell 1
                  COO –                             Channel
                                                 (1.2–1.5 nm)
          +
        NH 3                                     Cytosol 1
                                      Cell 2

                                      Cell membranes                   Transport In, Through and Between Cells II

                                                        Cytosol 2

                       1                             Ions, ATP, cAMP,
                                                     amino acids, etc.
                      Connexon  of Cell 1  3
         2
           Connexin                                                    Plate 1.9
                      Connexon  of Cell 2
           (27kDa)
                                          Channel open  Channel closed

         D.  Apical functional complex
         1                     Apical        Microvilli




                                             Tight            Para-
                                             junction        cellular
                                                            transport
                                   See (2)
                            Cell 2           Actin-
                        Zonula               myosin
                                             belt
                        adherens  Cell 1
          Epithelial cells (e.g., enterocytes)  Basolateral  N
                                                                N
                                             Occlusin

                                              E-cadherin
                               Myosin II
                         Actin         Adapter proteins
                                                           Ca 2+
              2
                                                                     19
                                                                     19
                                 Photos: H. Lodish. Reproduced with permission from Scientific American Books, New York, 1995.
       Despopoulos, Color Atlas of Physiology © 2003 Thieme
       All rights reserved. Usage subject to terms and conditions of license.
   27   28   29   30   31   32   33   34   35   36   37