Page 201 - Critical Care Notes
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                            Management
          ■ Surgical treatment may include colostomy or ileostomy.
          ■ Complications include peritonitis and sepsis.

              Intra-Abdominal Hypertension (IAH) or
            Abdominal Compartment Syndrome (ACS)
          IAH is characterized by an increase in abdominal pressure primarily caused by
          abdominal trauma, major burns, ruptured aortic aneurysm, mechanical intestin-
          al obstruction, abdominal operations with tight closures, or intraperitoneal dis-
          eases such as severe pancreatitis, intra-abdominal infection, ascites, abdominal
          tumors, or sepsis. It may lead to the development of abdominal compartment
          syndrome, shock, multiple organ failure, and death.
                           Pathophysiology
          Compression of intestinal tract → thrombosis and bowel wall edema → fluid
          accumulation and ↑ intra-abdominal pressure (IAP) →↓ arterial blood flow to
          abdominal organs → ischemia and anaerobic metabolism.
           Normal IAP = 0–5 mm Hg. Mean IAP in critically ill adults = 5–7 mm Hg.
           IAH is sustained/repeated ↑ of IAP >12 mm Hg.
           Abdominal perfusion pressure (APP) = MAP – IAP. Maintain at >60 mm Hg.
           An increase IAP to 20 mm Hg → ↓ in mesenteric perfusion by 40%. IAP 40 mm Hg
           → ↓ mesenteric perfusion by 70%.
                         Clinical Presentation
          ■ Wheezes, crackles, tachypnea, respiratory distress
          ■ Increase in abdominal girth
          ■ Syncope
          ■ Decreased urine output
          ■ Nausea, vomiting, melena
          ■ Signs and symptoms of multiple organ failure
                           Diagnostic Tests
          ■ Primarily by abdominal CT or abdominal ultrasound
          ■ Abdominal x-rays of little value


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