Page 58 - Critical Care Notes
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4223_Tab02_045-106  29/08/14  10:00 AM  Page 52



                  CV

                           Diagnostic Tests
          ■ CT or MRI of chest, abdomen, and brain
          ■ 2-D echocardiogram or transesophageal echocardiogram
          ■ ECG
          ■ CBC
          ■ Cardiac biomarkers if appropriate
          ■ Serum BUN, creatinine, BMP
          ■ Urinalysis especially specific gravity, urine toxicology
          ■ Renal ultrasound if kidney involvement
          ■ Chest x-ray (if dyspnea or chest pain present)
                            Management
          ■ Administer O 2 to maintain PaO 2 >92%. Monitor ABGs.
          ■ Obtain VS: orthostatic BP every 5 min, then longer intervals. Arterial line
            recommended.
          ■ Check BP in both arms.
          ■ Palpate pulses in all extremities.
          ■ Provide continuous ECG monitoring and treatment of arrhythmias.
          ■ Assess cardiac, respiratory, and neurological status.
          ■ Administer analgesics for pain or headache.
          ■ First-line medical therapy: labetalol (Trandate) or esmolol (Brevibloc),
            adrenergic-receptor blockers with both selective alpha-adrenergic and
            nonselective beta-adrenergic receptor blocking actions.
          ■ Administer vasodilators: nitroprusside (Nipride) and nitroglycerin (NTG).
            Monitor thiocyanate levels with Nipride administration.
          ■ Consider fenoldopam (Corlopam), clevidipine (Cleviprex), or enalapril
            (Vasotec).
          ■ Avoid nitroprusside and hydralazine if hypertensive encephalopathy sus-
            pected. Labetalol, nicardipine, or esmolol preferred.
          ■ Propranolol (Inderal) is not recommended for hypertensive crisis.
          ■ Hypertensive emergency: IV route is preferred; reduce mean arterial pres-
            sure (MAP) by no more than 25% in the first hour; if stable, ↓ diastolic BP
            to 100–110 mm Hg over the next 2–6 hr.
          ■ If neurological complication develops, primary goal → maintain adequate
            cerebral perfusion, control HTN, minimize cerebral edema; ↓ BP by 10% but
            no more than 20%–30% from initial reading.
          ■ Hypertensive urgency: Give po meds; ↓ BP in 24–48 hr; use short-acting
            agents: captopril (Capoten) or clonidine (Catapres).
          ■ Provide a quiet environment with low lighting. Cluster activities to provide
            rest and sleep.
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