Page 652 - Clinical Application of Mechanical Ventilation
P. 652

618    Chapter	19


                                            Initial Settings


                                            On the basis of clinical and laboratory data, a decision was made to assist the pa-
                          In the alert and coopera-  tient’s ventilation. In lieu of endotracheal intubation, bilevel positive airway pres-
                        tive patient with intact airway
                        defenses, noninvasive ventila-  sure (bilevel PAP or BiPAP®) was initiated via nasal mask at the settings below.
                        tion can provide ventilatory   The IPAP and EPAP levels were titrated to 15/5 cm H O resulting in an SpO  of
                        support without the risks                                         2                    2
                        associated with intubation.  around 90%.

                                                 Mode         Spontaneous
                                                 IPAP         15 cm H O
                                                                      2
                                                 EPAP         5 cm H O
                                                                     2
                                                 Sup. O 2     2 L/min

                                             The patient was poorly compliant with the therapy, removing the mask frequently,
                                            complaining of “not getting enough air.” After one hour, an arterial blood gas was
                                            obtained and revealed the following:

                                                 pH           7.25
                                                 PaCO 2       80 mm Hg
                                                 PaO 2        56 mm Hg
                                                       -
                                                 HCO          34 mEq/L
                                                      3
                                                 BE           13
                                                 SaO 2        86%
                                                 Hb           16 g/dL
                                                 HBCO         2%

                                             On the basis of the worsening ventilatory failure despite noninvasive ventilatory
                                            assistance, the patient was intubated with a size 8.5 endotracheal tube, and volume-
                                            controlled ventilation was initiated on the following settings:
                                                 Mode         CMV
                                                 V T          750 mL
                                                 f            10/min
                                                 Flow         55 L/min
                                                 F O 2        0.40
                                                  I
                                                 PEEP         5 cm H O
                                                                     2
                                                 Flow Trigger  3 L/min

                                             After 30 min, an arterial blood gas was obtained and revealed the following:

                                                 pH           7.37
                                                 PaCO 2       65 mm Hg
                                                 PaO 2        88 mm Hg
                                                       -
                                                 HCO          36 mEq/L
                                                      3
                                                 BE           16
                                                 SaO 2        96%
                                                 Hb           16 g/dL
                                                 HBCO         1%






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