Page 691 - Clinical Application of Mechanical Ventilation
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Case	Studies  657




















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                                             Figure 19-6  Myathensia gravis. Aspiration of barium on the left side (1) is seen. The right 
                                             hemidiaphragm is flat with a poorly defined costophrenic angle (2). This condition may be caused by 
                                             pleural effusion.
                                             Initial Settings


                                             The patient was initially placed on volume-controlled ventilation with the following
                            Glasgow coma score of   settings: CMV 16/min, V  750 mL, F O  80%, PEEP 0 cm H O. The patient had
                          #8 indicates severe brain in-            T          I  2                 2
                          jury or neurological deficit. A   the following ABG results:
                          score of 15 rules out presence
                          of neurological deficit.     pH       7.47
                                                   PaCO 2       43 mm Hg
                                                   PaO 2        168 mm Hg
                            The chest radiograph      SaO       97%
                          shows aspiration of barium in   2
                                                        -
                          the left lower lobe.     HCO          30.5 mEq/L
                                                        3
                                                   Mode         CMV
                                                   f            16/min
                                                   V            750 mL
                            PaO 2  168 mm Hg is too   T
                          high and the F I O 2  should be      F O 2   80%
                                                    I
                          decreased.               PEEP         0 cm H O
                                                                       2
                                             Patient Management


                                             (Day 1) The patient was continued on mechanical ventilation and the F O  was
                                                                                                             I
                                                                                                               2
                                             weaned to 40%, with the following results:
                                                   pH           7.58
                                                   PaCO 2       21 mm Hg
                            PaCO 2  21 mm Hg is too      PaO    122 mm Hg
                          low and the CMV frequency    2
                          should be decreased.     SaO 2        96%
                                                        -
                                                   HCO          19.1 mEq/L
                                                        3
                                                   Mode         CMV





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