Page 724 - Clinical Application of Mechanical Ventilation
P. 724

690    Appendix 1


                                            NORMAL VALUE
                                            CO 5 4 to 8 L/min

                                            EXAMPLE
                                            Given: Body surface area   5 1.6 m 2
                                            Arterial O  content     5 20 vol %
                                                    2
                                            Mixed venous O  content  5 15 vol %
                                                          2

                                                    O  consumption
                                               CO =   2
                                                     C O - C O   2
                                                         2
                                                      a
                                                               v
                                                      130 * BSA
                                                   =
                                                    C O - C O   2
                                                        2
                                                      a
                                                               v
                                                      130 * 1.6
                                                   =
                                                    20% - 15%
                                                    208
                                                   =
                                                     5%

                                                     208
                                                   =
                                                    0.05

                                                 54160 mL/min or 4.16 L/min


                                       C.  CEREBRAL PERFuSION PRESSuRE

                                            EQUATION
                                            CPP 5 MAP 2 ICP


                                            CPP :  Cerebral Perfusion Pressure
                                            MAP:  Mean Arterial Pressure
                                             ICP:  Intracranial Pressure

                                            NORMAL VALUE
                                            70 to 80 mm Hg

                                            EXAMPLE
                                            Calculate the CPP given the following data: MAP 5 90 mm Hg, ICP 5 14 mm
                                            Hg. Is the calculated CPP within normal limits?


                                            CPP  5 MAP 2 ICP
                                                     590 mm Hg 214 mm Hg
                                                     576 mm Hg

                                            CPP is within normal limit of 70 to 80 mm Hg






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