Page 726 - Clinical Application of Mechanical Ventilation
P. 726

692    Appendix 1


                                                      500
                                                   =
                                                    20 - 5
                                                    500
                                                   =
                                                     15
                                                   = 33.3 or 33 mL/cm H O
                                                                      2

                                       F.  CORRECTED TIDAL VOLumE (V )
                                                                                 T
                                            EQUATION
                                            Corrected V  5 Expired V  2 Tubing Volume
                                                                   T
                                                      T
                                               Expired V  :  Expired tidal volume in mL
                                                        T
                                            Tubing volume :   Volume “lost” in tubing during inspiratory phase (Pressure change 3
                                                           tubing compression factor)
                                            EXAMPLE
                                                                    Expired V  5 650 mL
                                                                            T
                                                        Peak inspiratory pressure 5 25 cm H O
                                                                                        2
                                            Positive end-expiratory pressure (PEEP) 5 5 cm H O
                                                                                       2
                                                       Tubing compression factor 5 3 mL/cm H O
                                                                                          2
                                            Calculate the corrected tidal volume.
                                            Tubing volume 5 Pressure Change 3 3 mL/cm H O
                                                                                       2
                                                         5 (25 – 5) cm H O 3 3 mL/cm H O
                                                                        2
                                                                                        2
                                                         5 20 3 3
                                                         5 60 mL
                                            Corrected V  5 Expired V  2 Tubing Volume
                                                                   T
                                                      T
                                                        5 650 2 60
                                                        5 590 mL

                                       G.  DEADSPACE TO TIDAL VOLumE RATIO (V /V )
                                                                                                  T
                                                                                             D
                                            EQUATION
                                            V D  =  (P CO - P CO )
                                                                  2
                                                              E
                                                    a
                                                        2
                                            V T         P CO 2
                                                         a
                                            V /V  :  Deadspace to tidal volume ratio in %
                                                 T
                                              D
                                             P CO  :  Arterial carbon dioxide tension in mm Hg
                                                  2
                                              a
                                            P CO  :  Mixed expired carbon dioxide tension in mm Hg
                                             E
                                                  2
                                            NORMAL VALUE
                                            20% to 40% in patients breathing spontaneously
                                            40% to 60% in patients receiving mechanical ventilation
                                            EXAMPLE
                                            Given: P CO  5 40 mm Hg
                                                       2
                                                   a
                                                 P CO  5 30 mm Hg
                                                   E
                                                       2



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