Page 205 - AACN Essentials of Critical-Care Nursing Pocket Handbook, Second Edition

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Usual Sampling Time IV: Immediately after IV loading dose: anytime during continuous infusion IV: Immediately after IV loading dose: anytime during continuous infusion

Trough: Just before next dose Peak: 8-12 hours after administered dose Trough: Just before next dose Trough: Just before next dose Trough: Just before next dose Anytime during a continuous infusion Trough: Just before next dose Trough: Just b

Usual Therapeutic Range 0.5-2 mg/L 0.5-2 mcg/L 2-4 mg/L 0.2-1.0 mg/L 1.5-5 mg/L 0.5-2 mg/L Procainamide: 4-10 mg/L NAPA: 10-20 mg/L 2.5-5 mg/L 4-10 mg/L 4-12 mg/L 20-50 mcg/L 15-40 mg/L 10-20 mg/L 50-100 mg/L

Therapeutic Drug Monitoring (continued)

Drug Antiarrhythmics Amiodarone Digoxin Disopyramide Flecainide Lidocaine Mexiletine Procainamide/NAPA Quinidine Tocainide Anticonvulsants Carbamazepine Pentobarbital Phenobarbital Phenytoin Valproic acid
7.5