Page 202 - AACN Essentials of Critical-Care Nursing Pocket Handbook, Second Edition

Initial hypertension, then postural hypotension; nausea and vomiting; parotitis; catecholamine sensitivity Beta-blocker with class III properties; creatinine clearance generally contraindicated in WPW WPW

Comments proarrhythmic effects; QT prolongation Dose adjusted based on QTc interval and Hypotension; negative inotropy; conduction disturbances; increased digoxin level; Hypotension; less negative inotropy than verapamil; conduction distur

5-10 mg/kg IV boluses q10 min up to 30 mg/kg, then 0.5-2 mg/min 160 mg PO q8h 250-500 mcg orally twice a day IV bolus: 5-10 mg over 2-3 minutes (repeat in 30 min prn), continuous infusion: 2.5-5 mcg/kg/min PO: 40-160 mg PO q8h IV bolus: 0.

Dosage 80-160 mg PO q12h; may increase up to (repeatin 15 minutes prn with 0.35 mg/kg

Antiarrhythmic Agents (continued) Indications Refractory ventricular tachycardia and ventricular fibrillation Life-threatening ventricular arrythmias Conversion of atrial fibrillation Conversion of SVT; slowing ventricular rate in atrial fibrilla

Agents Bretylium Dofetilide Class IV (calcium channel antagonists) Verapamil Diltiazem
7.4 Sotalol