Page 87 - Color Atlas Of Pathophysiology (S Silbernagl Et Al, Thieme 2000)

A. Obstructive Lung Diseases
Normal Infection
Allergy
Cartilage Asthma
Ciliated Inflammation
cells
Histamine,
Goblet leukotrienes
cells
Bronchial
glands Disease
Muscles

Bronchioles (section) Lung
Obstructive

Mucus sekretion Mucosal edema Muscle contraction

Inspiration Expiration Increased resistance to breathing 0.5 Abnormal Normal Plate 4.6
Alveolar pressure (kPa) 0 Normal Abnormal Work of Lung volume (L) Expiration Inspiration
+1

breathing
–1
0
–1
Time (s) 0.5 Resting level 0 Pleural pressure Ppl (kPa)
Lung volume (L)
Abnormal ventilation Expiratory Inspiratory Expiration requires
increased pressure
0
0 Pleural pressure –1
Ppl (kPa) Bronchial
compression
Hypoxia
Dyspnea
Labored
expiration
Compression of
Constriction of blood vessels
pulmonary vessels
Overdistension
of lungs

Pulmonary hypertension Emphysema

Right heart failure 77

Silbernagl/Lang, Color Atlas of Pathophysiology © 2000 Thieme
All rights reserved. Usage subject to terms and conditions of license.