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514  n  TRANSITIONAL CARE



           showing reductions in preventable hospital-  intervention  group  (intervention  =  $642,595
           izations for primary and coexisting illnesses,   vs. control = $1,238,928; p < .001). Time to first
   T       improvement  in  health  outcomes  after  dis-  readmission for any reason was increased in
           charge,  enhanced  patient  satisfaction,  and   the intervention group (log-ranked χ 1  = 11.1,
                                                                                    2
           reduction in total hospital costs.       p < .001; Naylor et al., 1999).
              The first randomized clinical trial, con-  The  third  clinical  trial  demonstrated
           ducted in 1994, demonstrated that transitional   potential for the TCM to decrease readmis-
           care has the potential to decrease rehospital-  sions  or  death,  decrease  mean  total  costs,
           izations, number of hospital days, and total   increase quality of care, and increase patient
           charges among 276 older medical and surgi-  satisfaction in 239 patients, ages 65 years and
           cal cardiac patients aged 70 and older (Naylor   older, hospitalized with heart failure (Naylor
           et  al.,  1994).  patients  were  randomized  to   et  al.,  2004).  patients  were  randomized  to
           receive  either  a  comprehensive  discharge   receive a 3-month advanced practice nurse–
           planning protocol specifically developed for   directed  intervention  or  control  group  who
           elders and implemented by geriatric clinical   received  routine  patient  management,  dis-
           specialists, or to a control group who received   charge planning, and standard home agency
           the  hospital’s  routine  discharge  plan.  The   care if referred. Time to first readmission or
           results  demonstrated  that  the  intervention   death  was  longer  in  intervention  patients
           medical patients had significantly decreased   (log-ranked χ    = 5.0, p = .026, Cox regression
                                                                2
           readmissions during the first 6 weeks (95%   incidence density ratio = 1.65, 95% confidence
           confidence interval [CI] = 25% to –1%, p = .04).    interval = 1.13–2.40). At  52  weeks, intervention
           Total  rehospitalization  days  were  fewer  for   patients had fewer readmissions (104 vs. 162,
           the  medical  intervention  group  than  for   p = .047) and lower mean total costs ($7636 vs.
           the  control  group  2  weeks  after  discharge   $12,481, p = .002). The intervention group also
           (p = .002) and between 2 and 6 weeks after   reported  short-term  improvements  in  over-
           discharge (p = .01). Total charges for health   all quality of life (2 weeks, p < .01; 12 weeks,
           care services after discharge for the medical   p  <  .05)  and  patient  satisfaction  (2  and
           intervention patients were $295,598 less than   6 weeks, p < .001; Naylor et al., 2004).
           the control group at 6 weeks (p = .02; Naylor   Ongoing  research  is  directed  toward
           et al., 1994).                           translating evidence into practice and extend-
              Results generated from the second clini-  ing transitional care into other populations.
           cal trial suggested that the TCM significantly   The team at the university of pennsylvania
           decreased  readmissions,  hospital  days,  and   has formed a partnership with leaders of the
           costs among 363 medical or surgical hospi-  Aetna Corporation to translate and integrate
           talized elders ages 65 and over (Naylor et al.,   the  TCM  for  use  in  everyday  practice  and
           1999).  patients  were  randomized  to  either   promote widespread adoption of the model
           an  advanced  practice  nurse–centered  dis-  by  demonstrating  its  effectiveness  with  a
           charge planning and home follow-up inter-  high-risk  Medicare  managed-care  popula-
           vention, or to a control group who received   tion in the mid Atlantic region. The evidence
           routine discharge planning. At 24 weeks, the   from this partnership is currently in analysis.
           intervention resulted in fewer total hospital   The  key  lessons,  however,  from  translating
           readmissions after the index hospitalization   research to practice, are the need to identify
           (intervention = 49 vs. control = 107; rank sum   strong champions, fit with the organization,
           test, p < .001), decreased hospital days (inter-  engage  key  stakeholders,  remain  flexible,
           vention  =  270  days  vs.  control  =  760  days;     assess and know the external climate, strat-
           p < p < .001), and lower reimbursement costs   egize  the  marketing  of  the  innovation  to
           for readmissions, acute care visits, and home   others,  establish  milestones,  and  measure
           visits  were  significantly  decreased  in  the   success (Naylor et al., 2009).
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