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Pregnancy and Postpartum Considerations 735



               TABLE 26.6  Management of Rhesus disease

               Blood tests and management      Rationale
               Kleihauer-Betke test or flow cytometry  Confirms that fetal blood has passed into the maternal circulation, also estimates the amount of
                                                fetal blood that has passed into the maternal circulation
               Indirect Coombs test            Screens maternal blood for anti-D antibodies that may pass through the placenta and cause
                                                haemolytic disease of the newborn
               Fetal blood (or umbilical cord blood) tests
               Direct Coombs test              Confirms that maternal anti-D antibodies are present in the fetal/newborn circulation
               Full blood count                Specifically, the haemoglobin level and platelet count to assess for anaemia
               Bilirubin                       Both total and indirect
               Antenatal Care
               Serial ultrasound and Doppler examinations  Detect signs of fetal anaemia such as increased blood flow velocities and monitor hydrops fetalis
               Quantitative analysis of maternal anti-RhD   An increasing titre level suggests fetal Rhesus disease
                 antibodies
               Intrauterine blood transfusion  Blood transfused into fetal umbilical vein, method of choice since the late 1980s, more effective
                                                than intraperitoneal transfusion
               Early delivery                  Usually post 36 weeks gestation
               Postnatal
               Phototherapy for neonatal jaundice in mild   Converts fat-soluble unconjugated bilirubin to water-soluble bilirubin that can be excreted by the
                 disease                        newborn
               Newborn exchange transfusion    Used if the neonate has moderate or severe disease; the blood for transfusion must be less than a
                                                week old, Rh negative, ABO compatible with both the fetus and the mother, and be cross
                                                matched against the mother’s serum




             D  deficiency  is  common,  yet  often  unrecognised  in
             critically  ill  patients. 196   Maternal  vitamin  D  deficiency   BOX 26.11  Routine postnatal observations
             is  associated  with  childhood  asthma  and  increased
             risk  of  osteoporotic  fracture  in  their  offspring. 197,198    l  Examination of breasts, looking for signs of engorgement,
             Due  attention  should  be  paid  to  a  pregnant  woman’s   mastitis, cracked nipples
             nutritional  status  in  ICU  as  poor  nutrition  during    l  Height, depth and texture of fundus, to ensure involution
             pregnancy is associated with many poor birth outcomes     is happening
             and  pregnancy  is  associated  with  increased  nutritional   l  Lochia, inspection of PV loss
             requirements. 199                                      l  Examination of perineum/wound for signs of healing
                                                                    l  Examination for signs of deep vein thrombosis; thrombo-
             CARING FOR POSTPARTUM                                     phylaxis is often indicated in a postpartum ICU woman
             WOMEN IN ICU                                           l  Mictrition and bowels; to ensure bowel and urinary pattern
                                                                       returning to normal
             Women admitted to ICU during the postpartum phase
             are  often  separated  from  their  newborn,  possibly  even
             transferred  to  another  hospital,  and  may  not  even  set
             eyes  on  their  child  for  days,  until  they  are  discharged     thrombophylaxis,  and  evaluation  of  her  psychological
                      3
             from ICU.  Specific care that should be provided to the   wellbeing and transition to motherhood (Box 26.11).
             postpartum woman includes observations, assistance to
             establish lactation as required and support for the mother   Uterine Involution
             by  early  nurturing  of  a  mother–infant  bond.  Finally,   The term ‘involution’ means the return of the uterus to
             attention to psychological needs of both the woman and   its normal size, tone and position. The vagina, ligaments
             her partner is an important part of care.            of the uterus and muscles of the pelvic floor also return
                                                                  to their pre-pregnant state during the involution process.
             ROUTINE POSTPARTUM OBSERVATIONS                      During this process, the lining of the uterus is cast off in
             Ongoing surveillance of a postpartum woman is essential   the lochia, more commonly referred to as PV loss, and is
             in addition to any ad hoc visits provided by a midwife.   later replaced by the new endometrium. Postdelivery of
             Routine maternity observations include assessment of the   the baby and postexpulsion of the placenta, the muscles
             fundus, PV loss and perineum, assessment of the breasts   of  the  uterus  constrict  the  blood  vessels,  so  the  blood
             and nipples, consideration of deep vein thrombosis and   circulating  within  the  uterus  is  dramatically  decreased.
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