Page 30 - Concise Pathology for Exam Preparation ( PDFDrive )

1 Cell Injury and Cell Death 15

Caseous necrosis

Dystrophic calcification

FIGURE 1.9. Section from a lymph node showing amorphous, eosinophilic and granular de-
bris (caseous necrosis) surrounded by a granulomatous reaction composed of Langhans giant
cells and chronic inflammatory cells (H&E; 1003).

FIGURE 1.10. Fat necrosis in the breast showing disruption of normal adipocytes and accumula-
tion of lipid-laden foamy histiocytes and a multinucleate giant cell (H&E; 2003).

Release of activated pancreatic lipases into pancreas and peritoneal cavity

Focal areas of destruction of fat and release of fatty acids

Released fatty acids combine with calcium (saponification)

Chalky white areas
FLOWCHART 1.10. Mechanism of evolution of enzymatic fat necrosis.

mebooksfree.com