Page 1011 - Williams Hematology ( PDFDrive )

986 Part VII: Neutrophils, Eosinophils, Basophils, and Mast Cells CHAPTER 64: Classification and Clinical Manifestations of Neutrophil Disorders 987

of differentiation (CD) 13 and CD15 phenotype with absent expression of the effect of cigarette usage. The oxidants, especially hypochlorous
of human leukocyte antigen-D related (HLA-DR) and CD34. acid and chloramines, released by the neutrophil are extremely short
lived and may play a role in tissue injury by inactivating several protease
QUALITATIVE NEUTROPHIL inhibitors in tissue fluids, permitting proteases, especially elastase, col-
lagenase, and gelatinase, to cause tissue injury. Thrombogenesis also has
ABNORMALITIES been ascribed to leukocyte products.

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