Page 1062 - Williams Hematology ( PDFDrive )
P. 1062

1036  Part VII:  Neutrophils, Eosinophils, Basophils, and Mast Cells  Chapter 66:  Disorders of Neutrophil Function  1037




                    135. Klebanoff SJ: Myeloperoxidase. Proc Assoc Am Physicians 111:383, 1999.    168. Baveye S, Elass E, Mazurier J, et al: Lactoferrin: A multifunctional glycoprotein involved
                    136. Klebanoff  SJ, Nathan  CF: Nitrite production  by stimulated  human  polymorphonu-  in the modulation of the inflammatory process. Clin Chem Lab Med 37:281, 1999.
                     clear leukocytes supplemented with azide and catalase. Biochem Biophys Res Commun     169. Farnaud S, Evans RW: Lactoferrin—A multifunctional protein with antimicrobial
                     197:192, 1993.                                        properties. Mol Immunol 40:395, 2003.
                    137. Eiserich JP, Baldus S, Brennan ML, et al: Myeloperoxidase, a leukocyte-derived vascular     170. Aguilera O, Ostolaza H, Quiros LM, et al: Permeabilizing action of an antimicrobial
                     NO oxidase. Science 296:2391, 2002.                   lactoferricin-derived peptide on bacterial and artificial membranes. FEBS Lett 462:273,
                    138. Savige J, Davies D, Falk RJ, et al: Antineutrophil cytoplasmic antibodies and associated   1999.
                     diseases: A review of the clinical and laboratory features. Kidney Int 57:846, 2000.    171. Nibbering PH, Ravensbergen E, Welling MM, et al: Human lactoferrin and peptides
                    139. Tervaert JW, Goldschmeding R, Elema JD, et al: Association of autoantibodies to mye-  derived from its N terminus are highly effective against infections with antibiotic-
                     loperoxidase with different forms of vasculitis. Arthritis Rheum 33:1264, 1990.  resistant bacteria. Infect Immun 69:1469, 2001.
                    140. Levy O, Elsbach P: Bactericidal/permeability-increasing protein in host defense and its     172. Flower DR: The lipocalin protein family: Structure and function. Biochem J 318:1,
                     efficacy in the treatment of bacterial sepsis. Curr Infect Dis Rep 3:407, 2007.  1996.
                    141. Alexander S, Bramson J, Foley R, et al: Protection from endotoxemia by adenoviral-    173. Kjeldsen L, Bainton DF, Sengelov H, et al: Identification of neutrophil gelatinase-
                     mediated gene transfer of human bactericidal/permeability-increasing protein. Blood   associated lipocalin as a novel matrix protein of specific granules in human neutrophils.
                     103:93, 2004.                                         Blood 83:799, 1994.
                    142. Balakrishnan A, Marathe SA, Joglekar M, et al: Bactericidal/permeability increasing     174. Yan L, Borregaard N, Kjeldsen L, et al: The high molecular weight urinary matrix metal-
                     protein:  A  multifaceted  protein  with  functions  beyond  LPS  neutralization.  Innate   loproteinase (MMP) activity is a complex of gelatinase B/MMP-9 and neutrophil gel-
                     Immun 19:339, 2013.                                   atinase-associated lipocalin (NGAL). Modulation of MMP-9 activity by NGAL. J Biol
                    143. Ganz T: Defensins: Antimicrobial peptides of innate immunity. Nat Rev Immunol 3:710,   Chem 276:37258, 2001.
                     2003.                                                175. Goetz DH, Holmes MA, Borregaard N, et al: The neutrophil lipocalin NGAL is a bac-
                    144. Selsted ME, Harwig SS, Ganz T, et al: Primary structures of three human neutrophil   teriostatic agent that interferes with siderophore-mediated iron acquisition. Mol Cell
                     defensins. J Clin Invest 76:1436, 1985.               10:1033, 2002.
                    145. Selsted ME, Tang YQ, Morris WL, et al: Purification, primary structures, and antibac-    176. Cowland JB, Muta T, Borregaard N: IL-1beta-specific up-regulation of neutrophil gel-
                     terial activities of beta-defensins, a new family of antimicrobial peptides from bovine   atinase-associated lipocalin is controlled by IkappaB-zeta. J Immunol 176:5559, 2006.
                     neutrophils. J Biol Chem 268:6641, 1993.             177. Flo TH, Smith KD, Sato S, et al: Lipocalin 2 mediates an innate immune response to
                    146. Tang YQ, Yuan J, Osapay G, et al: A cyclic antimicrobial peptide produced in primate   bacterial infection by sequestrating iron. Nature 432:917, 2004.
                     leukocytes by the ligation of two truncated alpha-defensins. Science 286:498, 1999.    178. Chan YR, Liu JS, Pociask DA, et al: Lipocalin 2 is required for pulmonary host defense
                    147. Perera NC, Wiesmuller KH, Larsen MT, et al: NSP4 is stored in azurophil granules and   against Klebsiella infection. J Immunol 182:4947, 2009.
                     released by activated neutrophils as active endoprotease with restricted specificity. J     179. Nairz M, Theurl I, Schroll A, et al: Absence of functional Hfe protects mice from inva-
                     Immunol 191:2700, 2013.                               sive Salmonella enterica serovar Typhimurium infection via induction of lipocalin-2.
                    148. Perera NC, Schilling O, Kittel H, et al: NSP4, an elastase-related protease in human   Blood 114:3642, 2009.
                     neutrophils with arginine specificity. Proc Natl Acad Sci U S A 109:6229, 2012.    180. Saiga H, Nishimura J, Kuwata H, et al: Lipocalin 2-dependent inhibition of mycobacte-
                    149. Almeida RP, Vanet A, Witko-Sarsat V, et al: Azurocidin, a natural antibiotic from   rial growth in alveolar epithelium. J Immunol 181:8521, 2008.
                     human neutrophils: Expression, antimicrobial activity, and secretion.  Protein Expr     181. Warszawska JM, Gawish R, Sharif O, et al: Lipocalin 2 deactivates macrophages and
                     Purif 7:355, 1996.                                    worsens pneumococcal pneumonia outcomes. J Clin Invest 123:3363, 2013.
                    150. Campanelli D, Detmers PA, Nathan CF, et al: Azurocidin and a homologous serine     182. Bao G, Clifton M, Hoette TM, et al: Iron traffics in circulation bound to a siderocalin
                     protease from neutrophils. Differential antimicrobial and proteolytic properties. J Clin   (Ngal)-catechol complex. Nat Chem Biol 6:602, 2010.
                     Invest 85:904, 1990.                                 183. Cellier M, Govoni G, Vidal S, et al: Human natural resistance-associated macrophage
                    151.  Flodgaard H, Ostergaard E, Bayne S, et al: Covalent structure of two novel neutrophile   protein: CDNA cloning, chromosomal mapping, genomic organization, and tissue-
                     leucocyte-derived proteins of porcine and human origin. Neutrophile elastase homologues   specific expression. J Exp Med 180:1741, 1994.
                     with strong monocyte and fibroblast chemotactic activities. Eur J Biochem 197:535, 1991.    184. Fleming A: On a remarkable bacteriolytic element found in tissues and excretions. Proc
                   152.  Gautam N, Olofsson AM, Herwald H, et al: Heparin-binding protein (HBP/CAP37): A    R Soc Lond B Biol Sci 93:306, 1922.
                     missing link in neutrophil-evoked alteration of vascular permeability. Nat Med 7:1123, 2001.    185. Selsted ME, Martinez RJ: Lysozyme: Primary bactericidin in human plasma serum
                    153. Tapper H, Karlsson A, Morgelin M, et al: Secretion of heparin-binding protein from   active against Bacillus subtilis. Infect Immun 20:782, 1978.
                     human neutrophils is determined by its localization in azurophilic granules and secre-    186. Tanida N, Onho N, Adachi Y, et al: Binding of lysozyme to synthetic monosaccharide
                     tory vesicles. Blood 99:1785, 2002.                   lipid A analogue, GLA60. Biol Pharm Bull 16:288, 1993.
                    154. Goldschmeding R, Tervaert JW, Dolman KM, et al: ANCA: A class of vasculitis-asso-    187. Takada K, Ohno N, Yadomae T: Binding of lysozyme to lipopolysaccharide suppresses
                     ciated autoantibodies against myeloid granule proteins: Clinical and laboratory aspects   tumor necrosis factor production in vivo. Infect Immun 62:1171, 1994.
                     and possible pathogenetic implications. Adv Exp Med Biol 297:129, 1991.    188. Keshav S, Chung P, Milon G, et al: Lysozyme is an inducible marker of macrophage
                    155. von Vietinghoff S, Tunnemann G, Eulenberg C, et al: NB1 mediates surface expression   activation in murine tissues as demonstrated by in situ hybridization.  J Exp Med
                     of the ANCA antigen proteinase 3 on human neutrophils. Blood 109:4487, 2007.  174:1049, 1991.
                    156. von Vietinghoff S, Eulenberg C, Wellner M, et al: Neutrophil surface presentation of     189. Sexton C, Buss D, Powell B, et al: Usefulness and limitations of serum and urine
                     the anti-neutrophil cytoplasmic antibody-antigen proteinase 3 depends on N-terminal   lysozyme levels in the classification of acute myeloid leukemia: An analysis of 208 cases.
                     processing. Clin Exp Immunol 152:508, 2008.           Leuk Res 20:467, 1996.
                    157. Skold S, Rosberg B, Gullberg U, et al: A secreted proform of neutrophil proteinase 3     190. Gudmundsson GH, Agerberth B, Odeberg J, et al: The human gene FALL39 and pro-
                     regulates the proliferation of granulopoietic progenitor cells. Blood 93:849, 1999.  cessing of the cathelin precursor to the antibacterial peptide LL-37 in granulocytes. Eur
                    158. Salvesen G, Enghild JJ: An unusual specificity in the activation of neutrophil serin pro-  J Biochem 238:325, 1996.
                     teinase zymogens. Biochemistry 29:5304, 1990.        191. Zanetti M: Cathelicidins, multifunctional peptides of the innate immunity. J Leukoc
                    159. Pham CT, Ivanovich JL, Raptis SZ, et al: Papillon-Lefevre syndrome: Correlating the   Biol 75:39, 2004.
                     molecular, cellular, and clinical consequences of cathepsin C/dipeptidyl peptidase I     192. Sorensen O, Arnljots K, Cowland JB, et al: The human antibacterial cathelicidin, hCAP-
                     deficiency in humans. J Immunol 173:7277, 2004.       18, is synthesized in myelocytes and metamyelocytes and localized to specific granules
                    160. Dalgic B, Bukulmez A, Sari S: Eponym: Papillon-Lefevre syndrome.  Eur J Pediatr   in neutrophils. Blood 90:2796, 1997.
                     170:689, 2011.                                       193. Frohm NM, Sandstedt B, Sorensen O, et al: The human cationic antimicrobial protein
                    161. Segal AW: How neutrophils kill microbes. Annu Rev Immunol 23:197, 2005.  (hCAP18), a peptide antibiotic, is widely expressed in human squamous epithelia and
                    162. Skubitz KM, Campbell KD, Skubitz AP: CD63 associates with CD11/CD18 in large   colocalizes with interleukin-6. Infect Immun 67:2561, 1999.
                     detergent-resistant complexes after translocation to the cell surface in human neu-    194. Heilborn JD, Nilsson MF, Kratz G, et al: The cathelicidin anti-microbial peptide LL-37
                     trophils. FEBS Lett 469:52, 2000.                     is involved in re-epithelialization of human skin wounds and is lacking in chronic ulcer
                    163. Saito N, Pulford KA, Breton-Gorius J, et al: Ultrastructural localization of the CD68   epithelium. J Invest Dermatol 120:379, 2003.
                     macrophage-associated antigen in human blood neutrophils and monocytes.  Am J     195. Sorensen OE, Cowland JB, Theilgaard-Monch K, et al: Wound healing and expression
                     Pathol 139:1053, 1991.                                of antimicrobial peptides/polypeptides in human keratinocytes, a consequence of com-
                    164. Mirinics ZK, Calafat J, Udby L, et al: Identification of the presenilins in hematopoietic   mon growth factors. J Immunol 170:5583, 2003.
                     cells with localization of presenilin 1 to neutrophil and platelet granules. Blood Cells     196. Sorensen OE, Gram L, Johnsen AH, et al: Processing of seminal plasma hCAP-18 to
                     Mol Dis 28:28, 2002.                                  ALL-38 by gastricsin: A novel mechanism of generating antimicrobial peptides in
                    165. Feuk-Lagerstedt E, Samuelsson M, Mosgoeller W, et al: The presence of stomatin in deter-  vagina. J Biol Chem 278:28540, 2003.
                     gent-insoluble domains of neutrophil granule membranes. J Leukoc Biol 72:970, 2002.    197. Zaiou M, Nizet V, Gallo RL: Antimicrobial and protease inhibitory functions of the
                    166. Nanda A, Brumell JH, Nordstrom T, et al: Activation of proton pumping in human   human cathelicidin (hCAP18/LL-37) prosequence. J Invest Dermatol 120:810, 2003.
                     neutrophils occurs by exocytosis of vesicles bearing vacuolar-type H+-ATPases. J Biol     198. De Y, Chen Q, Schmidt AP, et al: LL-37, the neutrophil granule- and epithelial
                     Chem 271:15963, 1996.                                 cell-derived cathelicidin, utilizes formyl peptide receptor-like 1 (FPRL1) as a receptor
                    167. Masson PL, Heremans JF, Schonne E: Lactoferrin, an iron-binding protein in neu-  to chemoattract human peripheral blood neutrophils, monocytes, and T cells. J Exp
                     trophilic leukocytes. J Exp Med 130:643, 1969.        Med 192:1069, 2000.







          Kaushansky_chapter 66_p1005-1042.indd   1037                                                                  9/21/15   10:48 AM
   1057   1058   1059   1060   1061   1062   1063   1064   1065   1066   1067