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Index 1355
Septic shock, 229f, 236, 236t, 259, 563 pulmonary hypertension, 910–911, 911f Solid organ infiltration, 868
in pregnancy, 1260–1261, 1260t sepsis and meningitis, 911 Soluble clotting factors, coagulation cascade
Sequential Organ Failure Assessment (SOFA) splenic sequestration and infarction, and, 846–847, 847t
scoring system, 85, 88, 89 911–912 Soluble triggering receptor expressed on
sepsis and, 568–569 stroke, 911 myeloid cells, sepsis and, 567
Serotonin syndrome, 560, 561t treatments, 912–914 Source control, for sepsis, 570
Severe sepsis, 937–938 analgesics, 912–913, 912t, 913t South American hemorrhagic fevers, 739
Severity index score, 568, 568t glucocorticoids, 914 Specificity of test, 47
Shingles, 670 hydroxyurea, 914 Specific metabolic disorders, acid-base
Shock, 249–262 incentive spirometry, 913 balance and, 969–970
adrenal, 238 investigational, 914 Spectrum of disability, clinical phenotypes in
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anaphylactic, 238, 260 oxygen and fluids, 912 critical illness and, 107–108, 108f
cardiogenic, 229f, 236–237, 256–257t, transfusion, 913–914, 913t, 914t Spider bite, 1222–1223
258–259, 306–307, 306f Silent ischemia, 295 Spinal cord injuries, 1178
circulatory, 243 Simple hemopneumothorax, 1160 Spinal injuries, 1137–1152, 1138t, 1139f
defined, 249–250 Simplified acute physiology score, airway, breathing, and respiratory issues,
electric, 1176 sepsis and, 568 1142–1144
establishing working diagnosis of cause of, Simplified Acute Physiology Score (SAPS II) complications, 1143–1144, 1143f
249–250, 250f scoring system, 93, 94, 379 ventilator weaning and
hypovolemic, 237, 254–256, 254f, 255–256, Sinusitis, 524–525, 559 tracheostomy, 1144
255f, 260 nosocomial, 686 bleeding and transfusion issues, 1146
inflammatory component of, 260 Sinus tachycardia, 498 cervical spine clearance, 1150
multiple etiologies of, 238 Sirolimus, 1089, 1100 classification of vertebral injuries,
neurogenic, 238, 260 Skeletal system, sickle cell disease 1138–1139, 1140t
obstructive, 258 and, 907 diagnostic imaging, 1141–1142,
organ system pathophysiology of, Skin, sickle cell disease and, 907 1141f, 1142f
260–261 Skull fractures, 1122, 1122f epidemiology of, 1138
right heart dysfunction as cause of, 309 Sleep, 155–161 gastrointestinal tract issues, 1152
role of fluids in, 263 after intensive care, 161 general management issues after
septic, 229f, 236, 236t, 259, 563 architecture, 156–157, 157f acute, 1141
spinal, 1145–1146 circadian rhythmicity in critically ill genitourinary tract issues, 1152
therapeutic interventions and, 261 patient, 158–159 health care-associated infections, 1151
treatment of, 728 in critically ill patient, 159–161, 159t hemodynamic issues
types of, 254–256, 257t, 258–260 mechanical ventilation and, 159–160 autonomic dysreflexia, 1145
untreated, 261 physiologic changes during normal, cardiovascular complications and
urgent initial resuscitation, 250–254, 251t, 157–158 neurogenic shock, 1144–1146, 1145f
252f, 253t potential adverse effects of disruption in management of instability, 1145
Shock liver, 1001 critically ill patients, 158, 158t monitoring, 1144
Shock lung, 261 promoting, in intensive-care unit, 161 spinal shock, 1145–1146
Shock-wave lithotripsy, 213 sedation and, 160–161, 160t intensive care unit management, 1142
Sickle cell anemia, 903 sleep-wake regulation, 156 neurological outcome, 1152
Sickle cell disease, 902–914, 903f Sleep deprivation, 157 neuroprotection, 1150
baseline physiology, 904–905, Slow continuous ultrafiltration (SCUF), 933 neurosurgical management issues,
905t, 906ft Small bowel feeding, role of, 137 1146–1147, 1146f, 1147f, 1148f,
common clinical problems, 906–907 Small bowel obstruction, 1005–1006, 1149–1150, 1149f
eye disease, 906 1020–1021 nutritional support issues, 1151
heart disease, 906–907 Smallpox, 749–750, 1302 glycemic control, 1151
hepatobiliary, 907 Snake bite, 1222 primary versus secondary, 1139–1140
lung disease, 906 Snare device, 226 rehabilitation, 1152
renal, 907 Society of Interventional Radiology sedation issues, 1151
skeletal, 907 Guidelines, for use of inferior vena temperature regulation and hypothermia,
skin, 907 cava (IVC) filters, 221 1150–1151
splenic, 907 Sodium, 944–950 venous thromboembolism, 1151
stroke, 906 hypernatremia, 945–947, 946ft, 947f Spinal paralysis, 1320
vaso-occlusive pain crisis, 906 hyponatremia, 947–950, 947f, 948ft Spinal shock, 1145–1146
general background for, 902–903 metabolism, 944–945, 944t Spiritual support, in palliative care,
genetics and epidemiology, 903 Sodium nitroprusside, 364 122–123
homozygous, 903 Sodium thiosulfate, 1215 Spleen injuries, 1165
pathophysiology, 904, 904t, 905f Soft tissue infections, 688–695 Splenic abscess, 1082
special problems in intensive care unit, classification of, 688–690, 689t Splenic sequestration, 911–912
907–912, 907t major, 690–695 sickle cell disease and, 912
acute chest syndrome, 907–908, 908t, anaerobic cellulitis, 691 Splenic system, sickle cell disease
909f, 910, 910t cellulitis, 690–691 and, 907
perioperative management of, 912 myonecrosis, 694–695, 694f Splinter hemorrhages, 1299
priapism, 912 necrotizing fasciitis, 691–694, 692f, 693f SpO 2 , clinical uses of, 243
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