Page 298 - Clinical Hematology_ Theory _ Procedures ( PDFDrive )

282 PART 4 ■ Erythrocyte Disorders

BOX 15.2

Promegaloblast (Megaloblastic Rubriblast)

Examples of Conditions Contributing to

Cobalamin (Vitamin B ) De ciency
12

VITAMIN B DEFICIENCY
12
Basophilic Megaloblast (Megaloblastic Prorubricyte) D ( )

B m m B

L k

P m

G

Polychromatophilic Megaloblast (Megaloblastic Rubricyte) I m
F m

MEDICATIONS (INHIBITORS)

H

P m
Orthochromic Megaloblast (Megaloblastic Metarubricyte)

MALABSORPTION

A

G

Polychromatophilic Megalocyte (Megaloblastic Reticulocyte) D m

P m

R

F m m B m (Im -
Megalocyte (Oval Macrocyte)
G ä k m )

D - m B m
FIGURE 15.1 M m . (R

m A S, P K. Anderson’s Atlas o Hematology, INTESTINAL

P , PA: L W m & W k , , O m , x m ,

m .)
m

S
m m (F . . ). T Diphyllobothrium latum

m B m DNA ,

m . IMPAIRED UTILIZATION

T m . T m II m

, m RNA, INCREASED DEMAND

m . P

I :

Etiology

M m

( B x . ). M m m B PERNICIOUS ANEMIA

m

m ( ). O Epidemiology

m B V m B k

. I z m B - (IF) mm m

Diphyllobothrium latum E . O m k m

m B m - -

. P IF . T m

m - m . I

. M m , k IF m m

m , m m A Am L ,

m .

. I mm m m A

. N m , -

m B m m .